Particular activation phenotype of T cells expressing HLA-DR but not CD38 in GALT from HIV-controllers is associated with immune regulation and delayed progression to AIDS

The spontaneous control of HIV replication in HIV-controllers underlines the importance of these subjects for exploring factors related to delayed progression. Several studies have revealed fewer immune alterations and effector mechanisms related to viral control, mainly in peripheral blood, in thes...

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Veröffentlicht in:	Immunologic research 2016-06, Vol.64 (3), p.765-774
Hauptverfasser:	Gonzalez, Sandra M., Taborda, Natalia A., Correa, Luis A., Castro, Gustavo A., Hernandez, Juan C., Montoya, Carlos J., Rugeles, Maria T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acquired immune deficiency syndrome ADP-ribosyl Cyclase 1 - metabolism Adult AIDS Allergology Biomedical and Life Sciences Biomedicine Disease Progression Female Forkhead Transcription Factors - metabolism Genotype & phenotype HIV HIV - physiology HIV Infections - immunology HLA-DR Antigens - metabolism Human immunodeficiency virus Humans Immune system Immunology Immunomodulation Immunophenotyping Internal Medicine Intestines - immunology Intestines - virology Lymphocyte Activation Lymphoid Tissue - immunology Lymphoid Tissue - virology Male Medicine/Public Health Nuclear Receptor Subfamily 1, Group F, Member 3 - metabolism Original Article T-Lymphocytes, Regulatory - immunology T-Lymphocytes, Regulatory - virology Th17 Cells - immunology Th17 Cells - virology Viral Load Young Adult
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