Antiherpes simplex virus type 2 activity of the antimicrobial peptide subtilosin

AIMS: In this study, we evaluated the antiviral activity of subtilosin, a cyclical peptide isolated from Bacillus amyloliquefaciens, against herpes simplex virus type 2 (HSV‐2) in cell cultures and we investigated subtilosin mode of action. METHODS AND RESULTS: We determined, using a virus yield inh...

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Veröffentlicht in:	Journal of applied microbiology 2014-11, Vol.117 (5), p.1253-1259
Hauptverfasser:	Quintana, V.M, Torres, N.I, Wachsman, M.B, Sinko, P.J, Castilla, V, Chikindas, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals antimicrobial peptide antiviral activity Antiviral Agents - pharmacology Antiviral drugs antiviral properties Bacillus amyloliquefaciens bacteriocin bacteriocins Bacteriocins - pharmacology Biological and medical sciences Cell culture Cercopithecus aethiops fluorescent antibody technique Fundamental and applied biological sciences. Psychology glycoproteins herpes simplex virus Herpes simplex virus 2 Herpes viruses Herpesvirus 2, Human - drug effects Human herpesvirus 2 Humans mechanism of action microbicide Microbiology Peptides Peptides, Cyclic - pharmacology subtilosin Vero Cells virion viruses
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