Ethanol and Acetaldehyde After Intraperitoneal Administration to Aldh2-Knockout Mice-Reflection in Blood and Brain Levels

This paper reports, for the first time, on the analysis of ethanol (EtOH) and acetaldehyde (AcH) concentrations in the blood and brains of Aldh2-knockout (Aldh2-KO) and C57B6/6J (WT) mice. Animals were administrated EtOH (1.0, 2.0 or 4.0 g/kg) or 4-methylpyrazole (4-MP, 82 mg/kg) plus AcH (50, 100 o...

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Veröffentlicht in:	Neurochemical research 2016-05, Vol.41 (5), p.1029-1034
Hauptverfasser:	Jamal, Mostofa, Ameno, Kiyoshi, Tanaka, Naoko, Ito, Asuka, Takakura, Ayaka, Kumihashi, Mitsuru, Kinoshita, Hiroshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaldehyde - blood Acetaldehyde - metabolism Acetaldehyde - pharmacology Aldehyde Dehydrogenase, Mitochondrial - genetics Animals Biochemistry Biomedical and Life Sciences Biomedicine Brain - metabolism Cell Biology Ethanol - blood Ethanol - metabolism Ethanol - pharmacology Injections, Intraperitoneal Male Mice, Inbred C57BL Mice, Knockout Neurochemistry Neurology Neurosciences Original Paper
Online-Zugang:	Volltext
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