White matter microstructural damage and depressive symptoms in patients with mild cognitive impairment and cerebral small vessel disease: the VMCI-Tuscany Study

Background and purpose Disruption of cortical‐subcortical circuits related to small vessel disease (SVD) may predispose to depression in the elderly. We aimed to determine the independent association between white matter (WM) microstructural damage, evaluated with diffusion tensor imaging (DTI), and...

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Veröffentlicht in:	International journal of geriatric psychiatry 2016-06, Vol.31 (6), p.611-618
Hauptverfasser:	Pasi, Marco, Poggesi, Anna, Salvadori, Emilia, Diciotti, Stefano, Ciolli, Laura, Del Bene, Alessandra, Marini, Sandro, Nannucci, Serena, Pescini, Francesca, Valenti, Raffaella, Ginestroni, Andrea, Toschi, Nicola, Mascalchi, Mario, Inzitari, Domenico, Pantoni, Leonardo
Format:	Artikel
Sprache:	eng
Schlagworte:	Activities of Daily Living Aged Aged, 80 and over Analysis of Variance Atrophy - pathology Cerebral Cortex - pathology Cerebral Small Vessel Diseases - pathology Cognition & reasoning Cognitive Dysfunction - pathology Cognitive Dysfunction - psychology Depressive Disorder - pathology depressive symptoms Diffusion Tensor Imaging Female Geriatric Assessment - methods Geriatric psychiatry Geriatric psychology Humans Longitudinal Studies Magnetic Resonance Imaging Male Mental depression mild cognitive impairment Neuropsychological Tests Neuropsychology Psychiatric Status Rating Scales small vessel disease Stroke, Lacunar - pathology Temporal Lobe - pathology Vein & artery diseases White Matter - pathology White Matter - ultrastructure white matter microstructural damage
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