A new approach for improving epothilone B yield in Sorangium cellulosum by the introduction of vgb epoF genes

Epothilone B has drawn great attention due to its much stronger anticancer activity and weaker side effects compared with taxol. The relative low yield of epothilone B limited its application. In this study, we report the successful introduction of the vgb gene and the epoF gene into Sorangium cellu...

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