Tumor-necrosis factor impairs CD4 super(+) T cell-mediated immunological control in chronic viral infection

Persistent viral infections are characterized by the simultaneous presence of chronic inflammation and T cell dysfunction. In prototypic models of chronicity-infection with human immunodeficiency virus (HIV) or lymphocytic choriomeningitis virus (LCMV)-we used transcriptome-based modeling to reveal...

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Veröffentlicht in:	Nature immunology 2016-05, Vol.17 (5), p.593-603
Hauptverfasser:	Beyer, Marc, Abdullah, Zeinab, Chemnitz, Jens M, Maisel, Daniela, Sander, Jil, Lehmann, Clara, Thabet, Yasser, Shinde, Prashant V, Schmidleithner, Lisa, Kohne, Maren, Trebicka, Jonel, Schierwagen, Robert, Hofmann, Andrea, Popov, Alexey, Lang, Karl S, Oxenius, Annette, Buch, Thorsten, Kurts, Christian, Heikenwalder, Mathias, Faetkenheuer, Gerd, Lang, Philipp A, Hartmann, Pia, Knolle, Percy A, Schultze, Joachim L
Format:	Artikel
Sprache:	eng
Schlagworte:	Human immunodeficiency virus Lymphocytic choriomeningitis virus
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