Influence of bone mineral density measurement on fracture risk assessment tool® scores in postmenopausal Indian women
Aim Fracture risk assessment tool® calculations can be performed with or without addition of bone mineral density; however, the impact of this addition on fracture risk assessment tool® scores has not been studied in Indian women. Given the limited availability and high cost of bone mineral density...
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| Veröffentlicht in: | Post reproductive health 2016-03, Vol.22 (1), p.20-24 |
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| creator | Daswani, Bhavna Desai, Meena Mitra, Sumegha Gavali, Shubhangi Patil, Anushree Kukreja, Subhash Khatkhatay, M Ikram |
| description | Aim
Fracture risk assessment tool® calculations can be performed with or without addition of bone mineral density; however, the impact of this addition on fracture risk assessment tool® scores has not been studied in Indian women. Given the limited availability and high cost of bone mineral density testing in India, it is important to know the influence of bone mineral density on fracture risk assessment tool® scores in Indian women. Therefore, our aim was to assess the contribution of bone mineral density in fracture risk assessment tool® outcome in Indian women.
Methods
Apparently healthy postmenopausal Indian women (n = 506), aged 40–72 years, without clinical risk factors for bone disease, were retrospectively selected, and their fracture risk assessment tool® scores calculated with and without bone mineral density were compared.
Results
Based on WHO criteria, 30% women were osteoporotic, 42.9% were osteopenic and 27.1% had normal bone mineral density. Fracture risk assessment tool® scores for risk of both major osteoporotic fracture and hip fracture significantly increased on including bone mineral density (P 0.05, whereas, for hip fracture risk number of women eligible without bone mineral density was 2 and with bone mineral density was 17, P |
| doi_str_mv | 10.1177/2053369116628722 |
| format | Article |
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Fracture risk assessment tool® calculations can be performed with or without addition of bone mineral density; however, the impact of this addition on fracture risk assessment tool® scores has not been studied in Indian women. Given the limited availability and high cost of bone mineral density testing in India, it is important to know the influence of bone mineral density on fracture risk assessment tool® scores in Indian women. Therefore, our aim was to assess the contribution of bone mineral density in fracture risk assessment tool® outcome in Indian women.
Methods
Apparently healthy postmenopausal Indian women (n = 506), aged 40–72 years, without clinical risk factors for bone disease, were retrospectively selected, and their fracture risk assessment tool® scores calculated with and without bone mineral density were compared.
Results
Based on WHO criteria, 30% women were osteoporotic, 42.9% were osteopenic and 27.1% had normal bone mineral density. Fracture risk assessment tool® scores for risk of both major osteoporotic fracture and hip fracture significantly increased on including bone mineral density (P < 0.0001). When criteria of National Osteoporosis Foundation, US was applied number of participants eligible for medical therapy increased upon inclusion of bone mineral density, (for major osteoporotic fracture risk number of women eligible without bone mineral density was 0 and with bone mineral density was 1, P > 0.05, whereas, for hip fracture risk number of women eligible without bone mineral density was 2 and with bone mineral density was 17, P < 0.0001).
Conclusion
Until the establishment of country-specific medication intervention thresholds, bone mineral density should be included while calculating fracture risk assessment tool® scores in Indian women.</description><identifier>ISSN: 2053-3691</identifier><identifier>EISSN: 2053-3705</identifier><identifier>DOI: 10.1177/2053369116628722</identifier><identifier>PMID: 26826081</identifier><language>eng</language><publisher>London, England: SAGE Publications</publisher><subject>Absorptiometry, Photon ; Adult ; Aged ; Bone Density ; Female ; Femur Neck - diagnostic imaging ; Fractures ; Health risk assessment ; Hip Fractures - prevention & control ; Humans ; India ; Lumbar Vertebrae - diagnostic imaging ; Menopause ; Middle Aged ; Osteoporosis - diagnostic imaging ; Osteoporosis - drug therapy ; Osteoporotic Fractures - prevention & control ; Postmenopause ; Retrospective Studies ; Risk Assessment - methods ; Womens health</subject><ispartof>Post reproductive health, 2016-03, Vol.22 (1), p.20-24</ispartof><rights>The Author(s) 2016</rights><rights>The Author(s) 2016.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c313t-2466b56e6f5f63b19333e90a932057feeb0b6e227a1b8a4e222c5678e88cb2cd3</citedby><cites>FETCH-LOGICAL-c313t-2466b56e6f5f63b19333e90a932057feeb0b6e227a1b8a4e222c5678e88cb2cd3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://journals.sagepub.com/doi/pdf/10.1177/2053369116628722$$EPDF$$P50$$Gsage$$H</linktopdf><linktohtml>$$Uhttps://journals.sagepub.com/doi/10.1177/2053369116628722$$EHTML$$P50$$Gsage$$H</linktohtml><link.rule.ids>314,776,780,21798,27901,27902,43597,43598</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/26826081$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Daswani, Bhavna</creatorcontrib><creatorcontrib>Desai, Meena</creatorcontrib><creatorcontrib>Mitra, Sumegha</creatorcontrib><creatorcontrib>Gavali, Shubhangi</creatorcontrib><creatorcontrib>Patil, Anushree</creatorcontrib><creatorcontrib>Kukreja, Subhash</creatorcontrib><creatorcontrib>Khatkhatay, M Ikram</creatorcontrib><title>Influence of bone mineral density measurement on fracture risk assessment tool® scores in postmenopausal Indian women</title><title>Post reproductive health</title><addtitle>Post Reprod Health</addtitle><description>Aim
Fracture risk assessment tool® calculations can be performed with or without addition of bone mineral density; however, the impact of this addition on fracture risk assessment tool® scores has not been studied in Indian women. Given the limited availability and high cost of bone mineral density testing in India, it is important to know the influence of bone mineral density on fracture risk assessment tool® scores in Indian women. Therefore, our aim was to assess the contribution of bone mineral density in fracture risk assessment tool® outcome in Indian women.
Methods
Apparently healthy postmenopausal Indian women (n = 506), aged 40–72 years, without clinical risk factors for bone disease, were retrospectively selected, and their fracture risk assessment tool® scores calculated with and without bone mineral density were compared.
Results
Based on WHO criteria, 30% women were osteoporotic, 42.9% were osteopenic and 27.1% had normal bone mineral density. Fracture risk assessment tool® scores for risk of both major osteoporotic fracture and hip fracture significantly increased on including bone mineral density (P < 0.0001). When criteria of National Osteoporosis Foundation, US was applied number of participants eligible for medical therapy increased upon inclusion of bone mineral density, (for major osteoporotic fracture risk number of women eligible without bone mineral density was 0 and with bone mineral density was 1, P > 0.05, whereas, for hip fracture risk number of women eligible without bone mineral density was 2 and with bone mineral density was 17, P < 0.0001).
Conclusion
Until the establishment of country-specific medication intervention thresholds, bone mineral density should be included while calculating fracture risk assessment tool® scores in Indian women.</description><subject>Absorptiometry, Photon</subject><subject>Adult</subject><subject>Aged</subject><subject>Bone Density</subject><subject>Female</subject><subject>Femur Neck - diagnostic imaging</subject><subject>Fractures</subject><subject>Health risk assessment</subject><subject>Hip Fractures - prevention & control</subject><subject>Humans</subject><subject>India</subject><subject>Lumbar Vertebrae - diagnostic imaging</subject><subject>Menopause</subject><subject>Middle Aged</subject><subject>Osteoporosis - diagnostic imaging</subject><subject>Osteoporosis - drug therapy</subject><subject>Osteoporotic Fractures - prevention & control</subject><subject>Postmenopause</subject><subject>Retrospective Studies</subject><subject>Risk Assessment - methods</subject><subject>Womens health</subject><issn>2053-3691</issn><issn>2053-3705</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kc1KxDAUhYMoOqh7VxJw46aanzZJlzL4MzDgRtclzdxKtU3G3FaZl_IhfDKjMyoIrnJzz3fPTTiEHHF2xrnW54IVUqqSc6WE0UJskclnK5OaFdvfddL3yCHiI2OM85zxotwle0IZoZjhE_Iy8003gndAQ0Pr4IH2rYdoO7oAj-2woj1YHCP04AcaPG2idUO609jiE7WIgPilDSF0728UXYiAtPV0GXBISljaEZPfzC9a6-lrSL0DstPYDuFwc-6T-6vLu-lNNr-9nk0v5pmTXA6ZyJWqCwWqKRola15KKaFktpTpd7oBqFmtQAhteW1snirhCqUNGONq4RZyn5yufZcxPI-AQ9W36KDrrIcwYsW10VqpkomEnvxBH8MYfXpdJXLB80IYbhLF1pSLATFCUy1j29u4qjirPmOp_saSRo43xmPdw-Jn4DuEBGRrAO0D_G791_AD4XGV8w</recordid><startdate>201603</startdate><enddate>201603</enddate><creator>Daswani, Bhavna</creator><creator>Desai, Meena</creator><creator>Mitra, Sumegha</creator><creator>Gavali, Shubhangi</creator><creator>Patil, Anushree</creator><creator>Kukreja, Subhash</creator><creator>Khatkhatay, M Ikram</creator><general>SAGE Publications</general><general>SAGE PUBLICATIONS, INC</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>ASE</scope><scope>FPQ</scope><scope>K6X</scope><scope>K9.</scope></search><sort><creationdate>201603</creationdate><title>Influence of bone mineral density measurement on fracture risk assessment tool® scores in postmenopausal Indian women</title><author>Daswani, Bhavna ; Desai, Meena ; Mitra, Sumegha ; Gavali, Shubhangi ; Patil, Anushree ; Kukreja, Subhash ; Khatkhatay, M Ikram</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c313t-2466b56e6f5f63b19333e90a932057feeb0b6e227a1b8a4e222c5678e88cb2cd3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Absorptiometry, Photon</topic><topic>Adult</topic><topic>Aged</topic><topic>Bone Density</topic><topic>Female</topic><topic>Femur Neck - diagnostic imaging</topic><topic>Fractures</topic><topic>Health risk assessment</topic><topic>Hip Fractures - prevention & control</topic><topic>Humans</topic><topic>India</topic><topic>Lumbar Vertebrae - diagnostic imaging</topic><topic>Menopause</topic><topic>Middle Aged</topic><topic>Osteoporosis - diagnostic imaging</topic><topic>Osteoporosis - drug therapy</topic><topic>Osteoporotic Fractures - prevention & control</topic><topic>Postmenopause</topic><topic>Retrospective Studies</topic><topic>Risk Assessment - methods</topic><topic>Womens health</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Daswani, Bhavna</creatorcontrib><creatorcontrib>Desai, Meena</creatorcontrib><creatorcontrib>Mitra, Sumegha</creatorcontrib><creatorcontrib>Gavali, Shubhangi</creatorcontrib><creatorcontrib>Patil, Anushree</creatorcontrib><creatorcontrib>Kukreja, Subhash</creatorcontrib><creatorcontrib>Khatkhatay, M Ikram</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>British Nursing Index</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>British Nursing Index</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><jtitle>Post reproductive health</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Daswani, Bhavna</au><au>Desai, Meena</au><au>Mitra, Sumegha</au><au>Gavali, Shubhangi</au><au>Patil, Anushree</au><au>Kukreja, Subhash</au><au>Khatkhatay, M Ikram</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Influence of bone mineral density measurement on fracture risk assessment tool® scores in postmenopausal Indian women</atitle><jtitle>Post reproductive health</jtitle><addtitle>Post Reprod Health</addtitle><date>2016-03</date><risdate>2016</risdate><volume>22</volume><issue>1</issue><spage>20</spage><epage>24</epage><pages>20-24</pages><issn>2053-3691</issn><eissn>2053-3705</eissn><abstract>Aim
Fracture risk assessment tool® calculations can be performed with or without addition of bone mineral density; however, the impact of this addition on fracture risk assessment tool® scores has not been studied in Indian women. Given the limited availability and high cost of bone mineral density testing in India, it is important to know the influence of bone mineral density on fracture risk assessment tool® scores in Indian women. Therefore, our aim was to assess the contribution of bone mineral density in fracture risk assessment tool® outcome in Indian women.
Methods
Apparently healthy postmenopausal Indian women (n = 506), aged 40–72 years, without clinical risk factors for bone disease, were retrospectively selected, and their fracture risk assessment tool® scores calculated with and without bone mineral density were compared.
Results
Based on WHO criteria, 30% women were osteoporotic, 42.9% were osteopenic and 27.1% had normal bone mineral density. Fracture risk assessment tool® scores for risk of both major osteoporotic fracture and hip fracture significantly increased on including bone mineral density (P < 0.0001). When criteria of National Osteoporosis Foundation, US was applied number of participants eligible for medical therapy increased upon inclusion of bone mineral density, (for major osteoporotic fracture risk number of women eligible without bone mineral density was 0 and with bone mineral density was 1, P > 0.05, whereas, for hip fracture risk number of women eligible without bone mineral density was 2 and with bone mineral density was 17, P < 0.0001).
Conclusion
Until the establishment of country-specific medication intervention thresholds, bone mineral density should be included while calculating fracture risk assessment tool® scores in Indian women.</abstract><cop>London, England</cop><pub>SAGE Publications</pub><pmid>26826081</pmid><doi>10.1177/2053369116628722</doi><tpages>5</tpages></addata></record> |
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| ispartof | Post reproductive health, 2016-03, Vol.22 (1), p.20-24 |
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| source | MEDLINE; SAGE Complete |
| subjects | Absorptiometry, Photon Adult Aged Bone Density Female Femur Neck - diagnostic imaging Fractures Health risk assessment Hip Fractures - prevention & control Humans India Lumbar Vertebrae - diagnostic imaging Menopause Middle Aged Osteoporosis - diagnostic imaging Osteoporosis - drug therapy Osteoporotic Fractures - prevention & control Postmenopause Retrospective Studies Risk Assessment - methods Womens health |
| title | Influence of bone mineral density measurement on fracture risk assessment tool® scores in postmenopausal Indian women |
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