Predicting the Unpredictable: Drug-Induced QT Prolongation and Torsades de Pointes

Drug-induced long QT syndrome (diLQTS) and congenital LQTS (cLQTS) share many features, and both syndromes can result in life-threatening torsades de pointes (TdP). Our understanding of their mechanistic and genetic similarities has led to their improved clinical management. However, our inability t...

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Veröffentlicht in:Journal of the American College of Cardiology 2016-04, Vol.67 (13), p.1639-1650
Hauptverfasser: Schwartz, Peter J, Woosley, Raymond L
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Sprache:eng
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