Synthesis of the C1–C10 Fragment of Madeirolide A

The synthesis of a fully elaborated C1–C10 fragment of madeirolide A has been achieved via a strategy based on a series of stereospecific processes. The concise synthetic route also features an iridium-catalyzed visible light induced radical cyclization for construction of the THP ring and a palladi...

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Veröffentlicht in:	Organic letters 2016-05, Vol.18 (9), p.2154-2157
Hauptverfasser:	Hwang, Sunghyun, Baek, Inhwan, Lee, Chulbom
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Sprache:	eng
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creator	Hwang, Sunghyun Baek, Inhwan Lee, Chulbom
description	The synthesis of a fully elaborated C1–C10 fragment of madeirolide A has been achieved via a strategy based on a series of stereospecific processes. The concise synthetic route also features an iridium-catalyzed visible light induced radical cyclization for construction of the THP ring and a palladium-catalyzed glycosylation for formation of the α-cineruloside linkage.
doi_str_mv	10.1021/acs.orglett.6b00777
format	Article
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title	Synthesis of the C1–C10 Fragment of Madeirolide A
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