Metabolomics Study of Type 2 Diabetes Mellitus and the AntiDiabetic Effect of Berberine in Zucker Diabetic Fatty Rats Using Uplc-ESI-Hdms

The present study aimed to evaluate the pathogenesis of type 2 diabetes mellitus (T2DM) and the anti‐diabetic effect of berberine in Zucker diabetic fatty (ZDF) rats. A urinary metabolomics analysis was performed with ultra‐performance liquid chromatography/electrospray ionization synapt high‐defini...

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Veröffentlicht in:	Phytotherapy research 2016-05, Vol.30 (5), p.823-828
Hauptverfasser:	Dong, Yu, Chen, Yi-Tao, Yang, Yuan-Xiao, Zhou, Xiao-Jie, Dai, Shi-Jie, Tong, Jun-Feng, Shou, Dan, Li, Changyu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals berberine Berberine - chemistry Berberine - therapeutic use Chromatography, High Pressure Liquid - methods Diabetes Mellitus, Type 2 - drug therapy Drugs, Chinese Herbal - chemistry Drugs, Chinese Herbal - therapeutic use Humans Hypoglycemic Agents - chemistry Hypoglycemic Agents - therapeutic use Male metabolomics Metabolomics - methods pattern recognition approach Rats Rats, Zucker type 2 diabetes UPLC-ESI-HDMS Zucker diabetic fatty rats
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