Infiltrating epitheliosis of the breast: characterization of histological features, immunophenotype and genomic profile

Aims Infiltrating epitheliosis is a rare complex sclerosing lesion (CSL) of the breast, characterized by infiltrating ducts immersed in a scleroelastotic stroma and filled with cells having architectural and cytological patterns reminiscent of those of usual ductal hyperplasia. In this study we soug...

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Veröffentlicht in:	Histopathology 2016-06, Vol.68 (7), p.1030-1039
Hauptverfasser:	Eberle, Carey A, Piscuoglio, Salvatore, Rakha, Emad A, Ng, Charlotte K Y, Geyer, Felipe C, Edelweiss, Marcia, Sakr, Rita A, Weigelt, Britta, Reis-Filho, Jorge S, Ellis, Ian O
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Breast - metabolism Breast - pathology Breast Neoplasms - genetics Breast Neoplasms - metabolism Breast Neoplasms - pathology Carcinoma, Adenosquamous - genetics Carcinoma, Adenosquamous - metabolism Carcinoma, Adenosquamous - pathology Carcinoma, Intraductal, Noninfiltrating - genetics Carcinoma, Intraductal, Noninfiltrating - metabolism Carcinoma, Intraductal, Noninfiltrating - pathology Class I Phosphatidylinositol 3-Kinases - genetics complex sclerosing lesions Female Fibrocystic Breast Disease - genetics Fibrocystic Breast Disease - metabolism Fibrocystic Breast Disease - pathology High-Throughput Nucleotide Sequencing Humans Hyperplasia immunohistochemistry Immunophenotyping infiltrating epitheliosis Mammography massively parallel sequencing Middle Aged Mutation Papilloma - genetics Papilloma - metabolism Papilloma - pathology Sclerosis - genetics Sclerosis - metabolism Sclerosis - pathology Sequence Analysis, DNA
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