Can Epstein-Barr virus DNA load in nasopharyngeal brushings or whole blood predict recurrent nasopharyngeal carcinoma in a non-endemic region? A prospective nationwide study of the Dutch Head and Neck Oncology Cooperative Group

This study estimated the value of quantitative measurements of EBV markers in the clinical management of nasopharyngeal carcinoma in a non-endemic area. The aim was to predict prognosis and detect recurrent and residual disease. In 72 patients, EBV DNA load in blood and nasopharyngeal brushes, and I...

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Veröffentlicht in:	European archives of oto-rhino-laryngology 2016-06, Vol.273 (6), p.1557-1567
Hauptverfasser:	Stoker, Sharon D., Wildeman, Maarten A., Novalic, Zlata, Fles, Renske, van der Noort, Vincent, de Bree, Remco, Braunius, Weibel W., van den Broek, Guido B., Kreike, Bas, Kross, Kenneth W., Juwana, Hedy, Ramayanti, Octavia, Verkuijlen, Sandra A. W. M., de Boer, Jan Paul, Greijer, Astrid E., Middeldorp, Jaap M., Tan, I. Bing
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Disease-Free Survival DNA, Viral - blood DNA, Viral - isolation & purification Early Diagnosis Epstein-Barr Virus Infections - diagnosis Epstein-Barr Virus Nuclear Antigens - blood Female Head and Neck Head and Neck Surgery Herpesvirus 4, Human - genetics Herpesvirus 4, Human - isolation & purification Humans Male Medicine Medicine & Public Health Middle Aged Nasopharyngeal Neoplasms - diagnosis Nasopharyngeal Neoplasms - mortality Nasopharyngeal Neoplasms - virology Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - virology Neoplasm, Residual Netherlands Neurosurgery Otorhinolaryngology Prognosis Prospective Studies Viral Load
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