Schisandra chinensis extract ameliorates nonalcoholic fatty liver via inhibition of endoplasmic reticulum stress

Schisandra chinensis (Turcz.) Baill. (SC) is a traditional Chinese herbal medicine with diverse pharmacological activities for treatment of various human diseases. Endoplasmic reticulum (ER) stress is associated with the pathogenesis of nonalcoholic fatty liver disease (NAFLD). In this study, we inv...

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Veröffentlicht in:	Journal of ethnopharmacology 2016-06, Vol.185, p.96-104
Hauptverfasser:	Jang, Min-Kyung, Nam, Jeong Soo, Kim, Ji Ha, Yun, Ye-Rang, Han, Chang Woo, Kim, Byung Joo, Jeong, Han-Sol, Ha, Ki-Tae, Jung, Myeong Ho
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Dietary Fats - administration & dosage Dietary Fats - adverse effects Endoplasmic Reticulum - drug effects Endoplasmic reticulum stress Hep G2 Cells Humans Inflammation Lipid Metabolism - drug effects Lipogenesis Liver - drug effects Liver - metabolism Mice Mice, Inbred C57BL Non-alcoholic Fatty Liver Disease - chemically induced Non-alcoholic Fatty Liver Disease - drug therapy Nonalcoholic fatty liver disease Plant Extracts - chemistry Plant Extracts - pharmacology Random Allocation Schisandra - chemistry Schisandra chinensis Stress, Physiological - drug effects Triglyceride accumulation Tunicamycin - toxicity
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