The hypoxia-related signaling pathways of vasculogenic mimicry in tumor treatment

Abstract Tumors require a blood supply for survival, growth, and metastasis. It is widely accepted that the development of the tumor microcirculation compartment need the production of new blood vessels (angiogenesis). Vasculogenic mimicry (VM) is an alternative type of blood supplement independent...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2016-05, Vol.80, p.127-135
Hauptverfasser:	Li, Shuixian, Meng, Wen, Guan, Ziwei, Guo, Yuanling, Han, Xiuzhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy Epithelial-Mesenchymal Transition HIF-1a Humans Hypoxia Hypoxia - pathology Internal Medicine Medical Education Neoplasms - metabolism Neoplasms - pathology Neoplasms - therapy Neovascularization, Pathologic - metabolism Neovascularization, Pathologic - pathology Signal Transduction Signaling pathway Tumor treatment Vasculogenic mimicry
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