Magnetic and hydrophilic MWCNT/Fe composites as potential T sub(2)-weighted MRI contrast agents
In this work, functionalized Multiwall Carbon Nanotubes of specified length and containing well-defined iron particles (O-MWCNT/Fe) were prepared. A significant enhancement in contrast in Magnetic Resonance Imaging was found for the investigated composites. The magnetic characterization revealed the...
Gespeichert in:
| Veröffentlicht in: | Carbon (New York) 2015-11, Vol.94, p.1012-1020 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1020 |
|---|---|
| container_issue | |
| container_start_page | 1012 |
| container_title | Carbon (New York) |
| container_volume | 94 |
| creator | Maciejewska, Barbara M Warowicka, Alicja Baranowska-Korczyc, Anna Zaleski, Karol Zalewski, Tomasz Koziol, Krzysztof K Jurga, Stefan |
| description | In this work, functionalized Multiwall Carbon Nanotubes of specified length and containing well-defined iron particles (O-MWCNT/Fe) were prepared. A significant enhancement in contrast in Magnetic Resonance Imaging was found for the investigated composites. The magnetic characterization revealed the ferromagnetic nature of iron particles embedded within O-MWCNTs. The enhancement of the spin-spin relaxation time of MRI scans using hydrophilic O-MWCNT/Fe as potential contrast agents was estimated for selected dispersive media. Moreover, the cytotoxicity of the hybrids was studied in two cell lines, i.e. cancer cells (HeLa) and fibroblasts (GM07492). The intracellular impact of O-MWCNT/Fes in HeLa cells was observed after staining of selected organelles (nuclei and mitochondria). Significant changes in cell morphology were found for water soluble MWCNT/Fes with diameters above 30 nm. |
| doi_str_mv | 10.1016/j.carbon.2015.07.091 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_1786212570</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1786212570</sourcerecordid><originalsourceid>FETCH-proquest_miscellaneous_17862125703</originalsourceid><addsrcrecordid>eNqVyrFuwjAQgGEPrVRaeIMOHukQczaQhBkVtUMYUCTG6EiuiZGxQ85R1bdvhr5Ap1-_9AnxqkFp0OnqqmocLsErA3qrIFOw0w9iBgB5khqzfhLPzNdpN7nezERVYOsp2lqib2T30wyh76ybvjjvj-XqQLIOtz6wjcQSWfYhko8WnSwlj5eleUu-ybZdpEYWp89J-zggR4nt5HguHr_QMS3--iKWh_dy_5H0Q7iPxLG6Wa7JOfQURq50lqdGm20G63_QX-R_TcY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1786212570</pqid></control><display><type>article</type><title>Magnetic and hydrophilic MWCNT/Fe composites as potential T sub(2)-weighted MRI contrast agents</title><source>Elsevier ScienceDirect Journals Complete</source><creator>Maciejewska, Barbara M ; Warowicka, Alicja ; Baranowska-Korczyc, Anna ; Zaleski, Karol ; Zalewski, Tomasz ; Koziol, Krzysztof K ; Jurga, Stefan</creator><creatorcontrib>Maciejewska, Barbara M ; Warowicka, Alicja ; Baranowska-Korczyc, Anna ; Zaleski, Karol ; Zalewski, Tomasz ; Koziol, Krzysztof K ; Jurga, Stefan</creatorcontrib><description>In this work, functionalized Multiwall Carbon Nanotubes of specified length and containing well-defined iron particles (O-MWCNT/Fe) were prepared. A significant enhancement in contrast in Magnetic Resonance Imaging was found for the investigated composites. The magnetic characterization revealed the ferromagnetic nature of iron particles embedded within O-MWCNTs. The enhancement of the spin-spin relaxation time of MRI scans using hydrophilic O-MWCNT/Fe as potential contrast agents was estimated for selected dispersive media. Moreover, the cytotoxicity of the hybrids was studied in two cell lines, i.e. cancer cells (HeLa) and fibroblasts (GM07492). The intracellular impact of O-MWCNT/Fes in HeLa cells was observed after staining of selected organelles (nuclei and mitochondria). Significant changes in cell morphology were found for water soluble MWCNT/Fes with diameters above 30 nm.</description><identifier>ISSN: 0008-6223</identifier><identifier>DOI: 10.1016/j.carbon.2015.07.091</identifier><language>eng</language><subject>Biotechnology ; Carbon ; Contrast agents ; Fibroblasts ; Iron ; Magnetic resonance imaging ; Multi wall carbon nanotubes ; Particulate composites</subject><ispartof>Carbon (New York), 2015-11, Vol.94, p.1012-1020</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Maciejewska, Barbara M</creatorcontrib><creatorcontrib>Warowicka, Alicja</creatorcontrib><creatorcontrib>Baranowska-Korczyc, Anna</creatorcontrib><creatorcontrib>Zaleski, Karol</creatorcontrib><creatorcontrib>Zalewski, Tomasz</creatorcontrib><creatorcontrib>Koziol, Krzysztof K</creatorcontrib><creatorcontrib>Jurga, Stefan</creatorcontrib><title>Magnetic and hydrophilic MWCNT/Fe composites as potential T sub(2)-weighted MRI contrast agents</title><title>Carbon (New York)</title><description>In this work, functionalized Multiwall Carbon Nanotubes of specified length and containing well-defined iron particles (O-MWCNT/Fe) were prepared. A significant enhancement in contrast in Magnetic Resonance Imaging was found for the investigated composites. The magnetic characterization revealed the ferromagnetic nature of iron particles embedded within O-MWCNTs. The enhancement of the spin-spin relaxation time of MRI scans using hydrophilic O-MWCNT/Fe as potential contrast agents was estimated for selected dispersive media. Moreover, the cytotoxicity of the hybrids was studied in two cell lines, i.e. cancer cells (HeLa) and fibroblasts (GM07492). The intracellular impact of O-MWCNT/Fes in HeLa cells was observed after staining of selected organelles (nuclei and mitochondria). Significant changes in cell morphology were found for water soluble MWCNT/Fes with diameters above 30 nm.</description><subject>Biotechnology</subject><subject>Carbon</subject><subject>Contrast agents</subject><subject>Fibroblasts</subject><subject>Iron</subject><subject>Magnetic resonance imaging</subject><subject>Multi wall carbon nanotubes</subject><subject>Particulate composites</subject><issn>0008-6223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><recordid>eNqVyrFuwjAQgGEPrVRaeIMOHukQczaQhBkVtUMYUCTG6EiuiZGxQ85R1bdvhr5Ap1-_9AnxqkFp0OnqqmocLsErA3qrIFOw0w9iBgB5khqzfhLPzNdpN7nezERVYOsp2lqib2T30wyh76ybvjjvj-XqQLIOtz6wjcQSWfYhko8WnSwlj5eleUu-ybZdpEYWp89J-zggR4nt5HguHr_QMS3--iKWh_dy_5H0Q7iPxLG6Wa7JOfQURq50lqdGm20G63_QX-R_TcY</recordid><startdate>20151101</startdate><enddate>20151101</enddate><creator>Maciejewska, Barbara M</creator><creator>Warowicka, Alicja</creator><creator>Baranowska-Korczyc, Anna</creator><creator>Zaleski, Karol</creator><creator>Zalewski, Tomasz</creator><creator>Koziol, Krzysztof K</creator><creator>Jurga, Stefan</creator><scope>7SR</scope><scope>8FD</scope><scope>JG9</scope></search><sort><creationdate>20151101</creationdate><title>Magnetic and hydrophilic MWCNT/Fe composites as potential T sub(2)-weighted MRI contrast agents</title><author>Maciejewska, Barbara M ; Warowicka, Alicja ; Baranowska-Korczyc, Anna ; Zaleski, Karol ; Zalewski, Tomasz ; Koziol, Krzysztof K ; Jurga, Stefan</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_17862125703</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Biotechnology</topic><topic>Carbon</topic><topic>Contrast agents</topic><topic>Fibroblasts</topic><topic>Iron</topic><topic>Magnetic resonance imaging</topic><topic>Multi wall carbon nanotubes</topic><topic>Particulate composites</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Maciejewska, Barbara M</creatorcontrib><creatorcontrib>Warowicka, Alicja</creatorcontrib><creatorcontrib>Baranowska-Korczyc, Anna</creatorcontrib><creatorcontrib>Zaleski, Karol</creatorcontrib><creatorcontrib>Zalewski, Tomasz</creatorcontrib><creatorcontrib>Koziol, Krzysztof K</creatorcontrib><creatorcontrib>Jurga, Stefan</creatorcontrib><collection>Engineered Materials Abstracts</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><jtitle>Carbon (New York)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Maciejewska, Barbara M</au><au>Warowicka, Alicja</au><au>Baranowska-Korczyc, Anna</au><au>Zaleski, Karol</au><au>Zalewski, Tomasz</au><au>Koziol, Krzysztof K</au><au>Jurga, Stefan</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Magnetic and hydrophilic MWCNT/Fe composites as potential T sub(2)-weighted MRI contrast agents</atitle><jtitle>Carbon (New York)</jtitle><date>2015-11-01</date><risdate>2015</risdate><volume>94</volume><spage>1012</spage><epage>1020</epage><pages>1012-1020</pages><issn>0008-6223</issn><abstract>In this work, functionalized Multiwall Carbon Nanotubes of specified length and containing well-defined iron particles (O-MWCNT/Fe) were prepared. A significant enhancement in contrast in Magnetic Resonance Imaging was found for the investigated composites. The magnetic characterization revealed the ferromagnetic nature of iron particles embedded within O-MWCNTs. The enhancement of the spin-spin relaxation time of MRI scans using hydrophilic O-MWCNT/Fe as potential contrast agents was estimated for selected dispersive media. Moreover, the cytotoxicity of the hybrids was studied in two cell lines, i.e. cancer cells (HeLa) and fibroblasts (GM07492). The intracellular impact of O-MWCNT/Fes in HeLa cells was observed after staining of selected organelles (nuclei and mitochondria). Significant changes in cell morphology were found for water soluble MWCNT/Fes with diameters above 30 nm.</abstract><doi>10.1016/j.carbon.2015.07.091</doi></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0008-6223 |
| ispartof | Carbon (New York), 2015-11, Vol.94, p.1012-1020 |
| issn | 0008-6223 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1786212570 |
| source | Elsevier ScienceDirect Journals Complete |
| subjects | Biotechnology Carbon Contrast agents Fibroblasts Iron Magnetic resonance imaging Multi wall carbon nanotubes Particulate composites |
| title | Magnetic and hydrophilic MWCNT/Fe composites as potential T sub(2)-weighted MRI contrast agents |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-13T03%3A08%3A03IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Magnetic%20and%20hydrophilic%20MWCNT/Fe%20composites%20as%20potential%20T%20sub(2)-weighted%20MRI%20contrast%20agents&rft.jtitle=Carbon%20(New%20York)&rft.au=Maciejewska,%20Barbara%20M&rft.date=2015-11-01&rft.volume=94&rft.spage=1012&rft.epage=1020&rft.pages=1012-1020&rft.issn=0008-6223&rft_id=info:doi/10.1016/j.carbon.2015.07.091&rft_dat=%3Cproquest%3E1786212570%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1786212570&rft_id=info:pmid/&rfr_iscdi=true |