A method for analysis of wilfordmine in human plasma by liquid chromatography coupled with ion trap mass spectrometry

A simple and rapid liquid chromatography-ion trap mass spectrometric (LC-IT/MS) method has been developed and validated for quantification of wilfordmine in human plasma. After the protein precipitation was carried out by acetonitrile and the solution was cleaned by solid-phase extraction, the chrom...

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Veröffentlicht in:	Journal of chromatographic science 2015-01, Vol.53 (1), p.177-182
Hauptverfasser:	Zhou, Lixin, Zhu, Hao, Ouyang, Xiaokun, Zhao, Jinshun, Chen, Xiaohong
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetonitrile Alkaloids - blood Chromatography Chromatography, High Pressure Liquid - methods Drugs, Chinese Herbal - analysis Extraction Flow rate Human Humans Ionization Liquid chromatography Mass Spectrometry - methods Standard deviation
Online-Zugang:	Volltext
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