Pubertal exposure to di-(2-ethylhexyl) phthalate influences social behavior and dopamine receptor D2 of adult female mice

DEHP, one of the most commonly phthalates used in plastics and many other products, is an environmental endocrine disruptor (EED). Puberty is another critical period for the brain development besides the neonatal period and is sensitive to EEDs. Social behavior is organized during puberty, so the pr...

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Veröffentlicht in:	Chemosphere (Oxford) 2016-02, Vol.144, p.1771-1779
Hauptverfasser:	Wang, Ran, Xu, Xiaohong, Zhu, Qingjie
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Animals Anxiety Anxiety - chemically induced Chambers Corpus Striatum - drug effects Corpus Striatum - metabolism Di-(2-ethylhexyl) phthalate Diethylhexyl Phthalate - toxicity Dopamine Dopamine receptor D2 Endocrine Disruptors - toxicity Estradiol - blood Estrogen Receptor beta - metabolism Estrogen receptor β Exploratory Behavior - drug effects Exposure Extracellular Signal-Regulated MAP Kinases - metabolism Female Females Mice Mice, Inbred ICR Organ Size - drug effects Phthalates Receptors Receptors, Dopamine D2 - metabolism Sexual Maturation - physiology Social Behavior Uterus - drug effects Uterus - growth & development
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