Paper-based chemical and biological sensors: Engineering aspects
Remarkable efforts have been dedicated to paper-based chemosensors and biosensors over the last few years, mainly driven by the promise of reaching the best trade-off between performance, affordability and simplicity. Because of the low-cost and rapid prototyping of these sensors, recent research ha...
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Veröffentlicht in: | Biosensors & bioelectronics 2016-03, Vol.77, p.249-263 |
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description | Remarkable efforts have been dedicated to paper-based chemosensors and biosensors over the last few years, mainly driven by the promise of reaching the best trade-off between performance, affordability and simplicity. Because of the low-cost and rapid prototyping of these sensors, recent research has been focused on providing affordable diagnostic devices to the developing world. The recent progress in sensitivity, multi-functionality and integration of microfluidic paper-based analytical devices (µPADs), increasingly suggests that this technology is not only attractive in resource-limited environments but it also represents a serious challenger to silicon, glass and polymer-based biosensors. This review discusses the design, chemistry and engineering aspects of these developments, with a focus on the past few years.
•Focus on the engineering aspects (paper microfluidics, design and fabrication, surface chemistry).•Updates of the last three years in paper-based analytical devices.•New insight on the future, challenges and perspectives of paper-based analytical devices. |
doi_str_mv | 10.1016/j.bios.2015.09.038 |
format | Article |
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subjects | Biosensing Techniques - instrumentation Biosensor Biosensors Biotechnology Cellulose paper Chemoreceptors Chemosensor Conductometry - instrumentation Devices Diagnostic systems Disposable Equipment Equipment Design Equipment Failure Analysis Equipment Reuse Immunoassay - instrumentation Lab-On-A-Chip Devices Lateral flow assays Mathematical analysis Microfluidics Paper microfluidics Tradeoffs |
title | Paper-based chemical and biological sensors: Engineering aspects |
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