An activatable fluorescent probe for targeting cellular membrane through the biothiol-mediated hydrazone-to-pyrazole transformation

A non-fluorescent coumarin-hydrazone conjugate probe was transformed into a strongly fluorescent pyrazolyl coumarin through a thiol-mediated cyclization reaction with F/F0 50. Interestingly, the probe was initially expressed at the cellular cytoplasm but translocated into the membrane regions of cel...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Sensors and actuators. B, Chemical Chemical, 2015-05, Vol.211, p.245-249
Hauptverfasser:	Kim, Gun-Joong, Yoon, Doo-Ha, Yun, Mi-Yeon, Kwon, Hyockman, Ha, Hyun-Joon, Kim, Hae-Jo
Format:	Artikel
Sprache:	eng
Schlagworte:	Activatable probe Actuators Biothiol Cells (biology) Cellular Conjugates Coumarin Fluorescence Membrane-targeting Membranes Ratiometric probe Transformations
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!