Reaction of oxidized dopamine with endogenous cysteine residues in the human dopamine transporter

There is evidence to suggest that dopamine (DA) oxidizes to form dopamine ortho‐quinone (DAQ), which binds covalently to nucleophilic sulfhydryl groups on protein cysteinyl residues. This reaction has been shown to inhibit dopamine uptake, as well as other biological processes. We have identified sp...

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Veröffentlicht in:Journal of neurochemistry 2001-02, Vol.76 (4), p.1242-1251
Hauptverfasser: Whitehead, Rachel E., Ferrer, Jasmine V., Javitch, Jonathan A., Justice, Joseph B.
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Sprache:eng
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