Positive selection and high sensitivity test for MYD88 mutations using locked nucleic acid

Summary Introduction Detection of mutations in the myeloid differentiation primary response gene 88 (MYD88) has clinical implications on diagnosis and therapy, especially in patients with Waldenström's macroglobulinemia (WM) and IgM monoclonal gammopathy of unknown significance (IgM‐MGUS). We d...

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Veröffentlicht in:	International journal of laboratory hematology 2016-04, Vol.38 (2), p.133-140
Hauptverfasser:	Albitar, A., Ma, W., DeDios, I., Estella, J., Agersborg, S., Albitar, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over AS-PCR diffuse large B-cell lymphoma DNA Mutational Analysis Female Humans LNA Male MGUS Middle Aged Monoclonal Gammopathy of Undetermined Significance - diagnosis Monoclonal Gammopathy of Undetermined Significance - genetics Mutation MYD88 Myeloid Differentiation Factor 88 - genetics Oligonucleotides Polymerase Chain Reaction Reproducibility of Results Sensitivity Sensitivity and Specificity Sequence Analysis, DNA Waldenstrom Macroglobulinemia - diagnosis Waldenstrom Macroglobulinemia - genetics Waldenström's macroglobulinemia wild-type blocking PCR
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