Influence of CYP3A5 6986A > G and ABCB1 3435C > T Polymorphisms on Adverse Events Associated With Tacrolimus in Jordanian Pediatric Renal Transplant Patients

The aim of the study is to investigate the influence of ABCB1(3435) and CYP3A5(6986) polymorphisms, tacrolimus troughs and clinical factors on the time of adverse events associated with tacrolimus in pediatric kidney transplant patients. Clinical data, adverse events, tacrolimus troughs, correspondi...

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Veröffentlicht in:	Clinical pharmacology in drug development 2013-01, Vol.2 (1), p.67-78
Hauptverfasser:	Sy, Sherwin K.B., Singh, Rajendra P., Shilbayeh, Sireen, Zmeili, Rawan, Conrado, Daniela, Derendorf, Hartmut
Format:	Artikel
Sprache:	eng
Schlagworte:	ABCB1 adverse events Clinical outcomes CYP3A5 Genotype & phenotype p-glycoprotein Pediatrics risk factors tacrolimus Transplants & implants
Online-Zugang:	Volltext
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