Calcimimetic and Calcilytic Drugs: Feats, Flops, and Futures

The actions of extracellular Ca 2+ in regulating parathyroid gland and kidney functions are mediated by the extracellular calcium receptor (CaR), a G protein-coupled receptor. The CaR is one of the essential molecules maintaining systemic Ca 2+ homeostasis and is a molecular target for drugs useful...

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Veröffentlicht in:	Calcified tissue international 2016-04, Vol.98 (4), p.341-358
Hauptverfasser:	Nemeth, E. F., Goodman, W. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Calcimimetic Agents - therapeutic use Calcium Cell Biology Endocrine system Endocrinology Homeostasis Hypercalcemia - drug therapy Hyperparathyroidism - drug therapy Life Sciences Orthopedics Pharmacology Receptors, Calcium-Sensing - agonists Receptors, Calcium-Sensing - antagonists & inhibitors Review
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