Polydatin Induces Apoptosis and Inhibits Growth of Acute Monocytic Leukemia Cells

ABSTRACT Polydatin (PD), a component isolated from Polygonum cuspidatum, has various activities such as inhibiting platelet aggregation, lowering level of blood lipid, reducing lipid peroxidation, and so on. However, the antitumor activity of PD has been poorly reported. In the present study, effect...

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Veröffentlicht in:	Journal of biochemical and molecular toxicology 2016-04, Vol.30 (4), p.200-205
Hauptverfasser:	Wang, Chunmei, Luo, Yuan, Lu, Jie, Wang, Yingchao, Sheng, Guangyao
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Monocytic Leukemia Apoptosis Apoptosis - drug effects bcl-2-Associated X Protein - metabolism Cell Cycle Cell Line, Tumor Cell Proliferation - drug effects Cyclins - metabolism Glucosides - pharmacology Humans Leukemia Leukemia, Monocytic, Acute - metabolism Leukemia, Monocytic, Acute - pathology Polydatin Polygonum cuspidatum Proliferation Proto-Oncogene Proteins c-bcl-2 - metabolism S Phase - drug effects Stilbenes - pharmacology
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