Interactive mechanism between avian infectious bronchitis S1 protein T cell peptide and avian MHC I molecule

•To construct a 3D structure of the avian MHC–β2M complex.•Perform molecular docking of potential epitope peptide Sp6 from IBV S1 and the MHC–β2M complex.•Demonstrate the interactive mechanism between Sp6 and MHC. This study aims to construct a 3D structure of the avian major histocompatibility comp...

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Veröffentlicht in:	Virus research 2016-04, Vol.215, p.76-83
Hauptverfasser:	Zhu, Feng-zhu, Lu, Mei, Huang, Qing-hua, Huang, Yan-yan, Yang, Shao-hua, Cui, Yan-shun, Liu, Chang, Tan, Liugang, Kong, Zhengjie, Xu, Chuan-tian
Format:	Artikel
Sprache:	eng
Schlagworte:	Avian infectious bronchitis virus CD8-Positive T-Lymphocytes - immunology Cell Proliferation CTL epitope Epitopes, T-Lymphocyte - chemistry Epitopes, T-Lymphocyte - metabolism Flow Cytometry Histocompatibility Antigens Class I - chemistry Histocompatibility Antigens Class I - metabolism Homology modelling Infectious bronchitis virus Infectious bronchitis virus - immunology Interferon-gamma - biosynthesis Molecular Docking Simulation Protein Binding Real-Time Polymerase Chain Reaction Spike Glycoprotein, Coronavirus - chemistry Spike Glycoprotein, Coronavirus - metabolism
Online-Zugang:	Volltext
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