Three-dimensional assembly of tissue-engineered cartilage constructs results in cartilaginous tissue formation without retainment of zonal characteristics

Articular cartilage has limited regenerative capabilities. Chondrocytes from different layers of cartilage have specific properties, and regenerative approaches using zonal chondrocytes may yield better replication of the architecture of native cartilage than when using a single cell population. To...

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Veröffentlicht in:	Journal of tissue engineering and regenerative medicine 2016-04, Vol.10 (4), p.315-324
Hauptverfasser:	Schuurman, W., Harimulyo, E. B., Gawlitta, D., Woodfield, T. B. F., Dhert, W. J. A., van Weeren, P. R., Malda, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biomarkers - metabolism cartilage Cartilage, Articular - physiology Cells, Cultured chondrocytes Collagen Type I - metabolism Collagen Type II - metabolism DNA - metabolism fibre deposition Glycosaminoglycans - metabolism Horses Humans Immunohistochemistry Regenerative medicine scaffolds Tissue engineering Tissue Engineering - methods Tissue Scaffolds - chemistry zonal
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