NMR studies reveal a novel grab and release mechanism for efficient catalysis of the bacterial 2‐Cys peroxiredoxin machinery

In bacteria, an ensemble of alkyl hydroperoxide reductase subunits C (AhpC) and F (AhpF) is responsible for scavenging H₂O₂. AhpC donates electrons for the reduction of H₂O₂, which are provided after NADH oxidation by AhpF. The latter contains an N‐terminal domain (NTD), catalyzing the electron tran...

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Veröffentlicht in:The FEBS journal 2015-12, Vol.282 (23), p.4620-4638
Hauptverfasser: Nartey, Wilson, Basak, Sandip, Kamariah, Neelagandan, Manimekalai, Malathy S. S, Robson, Scott, Wagner, Gerhard, Eisenhaber, Birgit, Eisenhaber, Frank, Grüber, Gerhard
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Sprache:eng
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