Production of high titer attenuated poliovirus strains on the serum-free PER.C6 registered cell culture platform for the generation of safe and affordable next generation IPV

Background As poliovirus eradication draws closer, alternative Inactivated Poliovirus Vaccines (IPV) are needed to overcome the risks associated with continued use of the Oral Poliovirus Vaccine and of neurovirulent strains used during manufacture of conventional (c) IPV. We have previously demonstr...

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Veröffentlicht in:	Vaccine 2015-11, Vol.33 (48), p.6611-6616
Hauptverfasser:	Sanders, Barbara P, Oakes, Isabel de los Rios, van Hoek, Vladimir, Liu, Ying, Marissen, Wilfred, Minor, Philip D, Wimmer, Eckard, Schuitemaker, Hanneke, Custers, Jerome HHV, Macadam, Andrew, Cello, Jeronimo, Edo-Matas, Diana
Format:	Artikel
Sprache:	eng
Schlagworte:	Enterovirus Picornaviridae
Online-Zugang:	Volltext
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