Investigation of Pseudomonas aeruginosa quorum-sensing signaling system for identifying multiple inhibitors using molecular docking and structural analysis methodology

Pseudomonas aeruginosa is an opportunistic human pathogen and a common Gram-negative bacterium in hospital-acquired infections. It causes death in many burn victims, cystic-fibrosis and neutropenic-cancer patients. It is known that P. aeruginosa biofilm maturation and production of cell-associated a...

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Veröffentlicht in:	Microbial pathogenesis 2015-12, Vol.89, p.73-78
Hauptverfasser:	Soheili, Vahid, Bazzaz, Bibi Sedigheh Fazly, Abdollahpour, Nooshin, Hadizadeh, Farzin
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - isolation & purification Anti-Bacterial Agents - pharmacology Bacterial Proteins - antagonists & inhibitors Bacterial Proteins - chemistry Biofilm Docking Drug Discovery - methods Humans Molecular Docking Simulation NSAID Pseudomonas aeruginosa Pseudomonas aeruginosa - physiology Quorum Sensing
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