Different patterns of allelic imbalance in sporadic tumors and tumors associated with long-term exposure to gamma-radiation

•We compare the prevalence of genotypes of SNP in tumors and matched normal tissues.•We consider the effects of gamma-radiation on the risk of the development of cancer.•We showed the phenomenon of allelic imbalance in tumors associated with radiation.•We demonstrated the phenomenon of allelic imbal...

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Veröffentlicht in:	Mutation research. Genetic toxicology and environmental mutagenesis 2015-12, Vol.794, p.8-16
Hauptverfasser:	Litviakov, Nikolai V., Freidin, Maxim B., Sazonov, Aleksey E., Khalyuzova, Maria V., Buldakov, Mikhail A., Karbyshev, Mikhail S., Albakh, Еlena N., Isubakova, Daria S., Gagarin, Аleksey A., Nekrasov, Gennadiy B., Mironova, Elena B., Izosimov, Аndrey S., Takhauov, Ravil M., Karpov, Аndrei B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Allelic Imbalance Case-Control Studies Cell cycle DNA Repair Female Gamma rays Gamma Rays - adverse effects Gene Frequency Genes Genetic Association Studies Genetic Loci Genetic polymorphism Genotype Genotype & phenotype Humans Male Malignant tumor Middle Aged Mutation Neoplasms - etiology Neoplasms - genetics Occupational Exposure - adverse effects Polymorphism, Single Nucleotide Tumors γ-Radiation
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