Evaluation of novel antiproliferative controlled drug delivery system based on poly(2-hydroxypropyl acrylate/itaconic acid) hydrogels and nickel complex with Oxaprozin

A series of dual-sensitive poly(2-hydroxypropyl acrylate/itaconic acid) (P(HPA/IA)) hydrogels were synthesized and evaluated as potential highly effective antiproliferative drug delivery system. Investigated hydrophobic antiproliferative agent, Ni(II) complex with Oxaprozin, was successfully synthes...

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Veröffentlicht in:	Materials letters 2016-01, Vol.163, p.214-217
Hauptverfasser:	Babic, Marija M, Bozic, Bojan, Bozic, Biljana, Filipovic, Jovanka M, Uscumlic, Gordana S, Tomic, Simonida Lj
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylates Antiproliferative activity Antiproliferatives Biotechnology Cancer Controlled drug delivery Drug delivery systems Hydrogel Hydrogels In vitro testing Itaconic acid Transition metal drug
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