Large-scale screening for somatic mutations in lung cancer

In squamous-cell carcinoma and small-cell lung carcinomas, several novel driver mutations are being investigated as potentially actionable targets: amplification of FGFR1, PIK3CA,9 and the sequence of the entire 3·2 kb coding region of DDR2.5,10DDR2 mutations can be detected at a frequency of 3% in...

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Veröffentlicht in:	The Lancet (British edition) 2016-04, Vol.387 (10026), p.1354-1356
Hauptverfasser:	Rosell, Rafael, Karachaliou, Niki
Format:	Artikel
Sprache:	eng
Schlagworte:	Cancer therapies Carcinoma, Non-Small-Cell Lung - genetics Female Gene Expression Profiling Genotypes Humans Internal Medicine Kinases Lung cancer Lung Neoplasms - genetics Male Medical screening Mutation Public private partnerships
Online-Zugang:	Volltext
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