Substance P enhances EPC mobilization for accelerated wound healing

Wound healing is essential for the survival and tissue homeostasis of unicellular and multicellular organisms. The current study demonstrated that the neuropeptide substance P (SP) accelerated the wound healing process, particularly in the skin. Subcutaneous treatment of SP accelerated wound closing...

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Veröffentlicht in:	Wound repair and regeneration 2016-03, Vol.24 (2), p.402-410
Hauptverfasser:	Um, Jihyun, Jung, Nunggum, Chin, Sukbum, Cho, Younggil, Choi, Sanghyuk, Park, Ki-Sook
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Movement Chemokine CXCL12 Collagen - pharmacology Disease Models, Animal Drug Combinations Endothelial Progenitor Cells - drug effects Endothelial Progenitor Cells - pathology Extracellular Matrix - pathology Immunohistochemistry Laminin - pharmacology Male Mice Mice, Inbred C57BL Neovascularization, Physiologic - drug effects Neurotransmitter Agents - pharmacology Proteoglycans - pharmacology Substance P - pharmacology Vascular Endothelial Growth Factor A Wound Healing - drug effects Wounds and Injuries - drug therapy Wounds and Injuries - pathology
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