Evaluation of cannabinoid CB1 and CB2 receptors expression in mobile tongue squamous cell carcinoma: associations with clinicopathological parameters and patients’ survival

Cannabinoid receptors (CB1R and CB2R) constitute essential members of the endocannabinoid system (ECS) which participates in many different functions indispensable to homeostatic regulation in several tissues, exerting also antitumorigenic effects. The present study aimed to assess the clinical sign...

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Veröffentlicht in:	Tumor biology 2016-03, Vol.37 (3), p.3647-3656
Hauptverfasser:	Theocharis, Stamatios, Giaginis, Constantinos, Alexandrou, Paraskevi, Rodriguez, Jose, Tasoulas, Jason, Danas, Eugene, Patsouris, Efstratios, Klijanienko, Jerzy
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Aged Aged, 80 and over Biomarkers, Tumor - biosynthesis Biomedical and Life Sciences Biomedicine Cancer Research Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - surgery Female Humans Immunohistochemistry Kaplan-Meier Estimate Male Medical prognosis Middle Aged Multivariate Analysis Oral cancer Original Article Outcome Assessment (Health Care) - methods Outcome Assessment (Health Care) - statistics & numerical data Pathology Prognosis Proportional Hazards Models Receptor, Cannabinoid, CB1 - biosynthesis Receptor, Cannabinoid, CB2 - biosynthesis Sex Factors Tongue Neoplasms - metabolism Tongue Neoplasms - pathology Tongue Neoplasms - surgery Tumors
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