Comprehensive epidemiological and genotype–phenotype analyses in a large European sample with idiopathic achalasia

BACKGROUND AND AIMAlthough an eight-residue insertion in HLA-DQβ1 has been recently identified as a genetic risk factor for idiopathic achalasia, other risk factors are still unknown. In the present study, we carried out an epidemiological survey and a genotype–phenotype (G×P) analysis to gain furth...

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Veröffentlicht in:	European journal of gastroenterology & hepatology 2016-06, Vol.28 (6), p.689-695
Hauptverfasser:	Becker, Jessica, Niebisch, Stefan, Ricchiuto, Arcangelo, Schaich, Eva J, Lehmann, Gavin, Waltgenbach, Tobias, Schafft, Annette, Hess, Timo, Lenze, Frank, Venerito, Marino, Hüneburg, Robert, Lingohr, Philipp, Matthaei, Hanno, Seewald, Stefan, Scheuermann, Uwe, Kreuser, Nicole, Veits, Lothar, Wouters, Mira M, Gockel, Henning R, Lang, Hauke, Vieth, Michael, Müller, Michaela, Eckardt, Alexander J, von Rahden, Burkhard H.A, Knapp, Michael, Boeckxstaens, Guy E, Fimmers, Rolf, Nöthen, Markus M, Schulz, Henning G, Gockel, Ines, Schumacher, Johannes
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alleles Autoimmune Diseases - epidemiology Case-Control Studies Chickenpox - epidemiology Comorbidity Esophageal Achalasia - epidemiology Esophageal Achalasia - genetics Europe - epidemiology European Continental Ancestry Group - genetics Family Female Genotype Herpes Zoster - epidemiology Herpesvirus 3, Human Heterozygote HLA-DQ beta-Chains - genetics Humans Hypersensitivity - epidemiology Male Middle Aged Phenotype Pregnancy Pregnancy Complications - epidemiology Pregnancy Complications - genetics Psoriasis - epidemiology Sjogren's Syndrome - epidemiology Virus Diseases - epidemiology
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