The use of DNA double-strand break quantification in radiotherapy

DNA double-strand breaks (DSB) are an important direct consequence of treating cells with ionizingradiation. A variety of evidence points toward DSBs being the key damage type linked to radiation-induced lethality. In particular, the link between DSB and chromosome breakage, which in turn closely co...

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Veröffentlicht in:International journal of radiation oncology, biology, physics biology, physics, 2001-02, Vol.49 (2), p.373-377
Hauptverfasser: McMillan, Trevor J, Tobi, Simon, Mateos, Santiago, Lemon, Catherine
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Sprache:eng
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