Functional significance of transgelin-2 in uterine cervical squamous cell carcinoma

Aim Transgelin‐2 (TAGLN2) has previously been found to be highly expressed in uterine cervical squamous cell carcinoma (SCC) tissues by proteomic analyses. The present study investigated the role of TAGLN2 in the malignant behaviors of cervical SCC cells in vitro and in vivo, and the clinical signif...

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Veröffentlicht in:	The journal of obstetrics and gynaecology research 2016-05, Vol.42 (5), p.566-572
Hauptverfasser:	Yakabe, Kazuyuki, Murakami, Akihiro, Kajimura, Takuya, Nishimoto, Yuki, Sueoka, Kotaro, Sato, Shun, Nawata, Shugo, Sugino, Norihiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cancer progression Carcinoma, Squamous Cell - metabolism Carcinoma, Squamous Cell - pathology Carcinoma, Squamous Cell - physiopathology Cell Line, Tumor Cell Movement Cell Proliferation cervical squamous cell carcinoma Female Humans Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - metabolism Mice Mice, Inbred BALB C Mice, Nude Microfilament Proteins - metabolism Microfilament Proteins - physiology migration Muscle Proteins - metabolism Muscle Proteins - physiology transgelin-2 tumorigenesis Uterine Cervical Neoplasms - metabolism Uterine Cervical Neoplasms - pathology Uterine Cervical Neoplasms - physiopathology
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