Evidence That Anorectal Transplantation Is the Logical Treatment for Serious Anorectal Dysfunction and Permanent Colostomy
Abstract Anorectal dysfunction resulting in fecal incontinence or permanent colostomy is a current public health concern that strongly impairs patient quality of life. Present treatment options for this complex disease are expensive and usually ineffective. Anorectal transplantation is the logical t...
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| Veröffentlicht in: | Transplantation proceedings 2016-03, Vol.48 (2), p.497-498 |
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| container_title | Transplantation proceedings |
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| creator | Ferreira Galvao, F.H Araki, J Seid, V.E Waisberg, D.R Traldi, M.C Naito, M Araujo, B.C Lanchotte, C Chaib, E D'Albuquerque, L.A.C |
| description | Abstract Anorectal dysfunction resulting in fecal incontinence or permanent colostomy is a current public health concern that strongly impairs patient quality of life. Present treatment options for this complex disease are expensive and usually ineffective. Anorectal transplantation is the logical treatment for fecal incontinence and permanent colostomy. This procedure has been clinically effective in a few cases reported in the medical literature. Furthermore, experiments in rats, pigs, and dogs have shown promising results, with functional recovery of the graft. In this article we describe the scientific evidence that anorectal transplantation may be an important option for treating anorectal dysfunction. |
| doi_str_mv | 10.1016/j.transproceed.2015.10.082 |
| format | Article |
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Present treatment options for this complex disease are expensive and usually ineffective. Anorectal transplantation is the logical treatment for fecal incontinence and permanent colostomy. This procedure has been clinically effective in a few cases reported in the medical literature. Furthermore, experiments in rats, pigs, and dogs have shown promising results, with functional recovery of the graft. In this article we describe the scientific evidence that anorectal transplantation may be an important option for treating anorectal dysfunction.</description><identifier>ISSN: 0041-1345</identifier><identifier>EISSN: 1873-2623</identifier><identifier>DOI: 10.1016/j.transproceed.2015.10.082</identifier><identifier>PMID: 27109986</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Animals ; Colostomy ; Dogs ; Fecal Incontinence - surgery ; Humans ; Quality of Life ; Rats ; Recovery of Function ; Rectum - transplantation ; Surgery ; Swine</subject><ispartof>Transplantation proceedings, 2016-03, Vol.48 (2), p.497-498</ispartof><rights>Elsevier Inc.</rights><rights>2016 Elsevier Inc.</rights><rights>Copyright © 2016 Elsevier Inc. 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In this article we describe the scientific evidence that anorectal transplantation may be an important option for treating anorectal dysfunction.</description><subject>Animals</subject><subject>Colostomy</subject><subject>Dogs</subject><subject>Fecal Incontinence - surgery</subject><subject>Humans</subject><subject>Quality of Life</subject><subject>Rats</subject><subject>Recovery of Function</subject><subject>Rectum - transplantation</subject><subject>Surgery</subject><subject>Swine</subject><issn>0041-1345</issn><issn>1873-2623</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkk9v1DAQxS0EokvhK6CIE5csnjh_HA5I1bZApZVA6t4tx55QL4ldbKfS9tNj77ZSxYmTZb33Zjw_DyEfgK6BQvtpv45e2nDnnULU64pCk4Q15dULsgLesbJqK_aSrCitoQRWN2fkTQh7mu5VzV6Ts6oD2ve8XZGHq3uj0SosdrcyFhfWeVRRTsXu2GKSNsponC2uQxFvsdi6X0YdZZRxRhuL0fniBr1xS3gWvzyEcbHqGJVWFz_Rz9Jm_8ZNLkQ3H96SV6OcAr57PM_J7uvVbvO93P74dr252JaqZk0s2dBIbDWrOSC0oCRlVYea6Z7B2Ned1hIZKK4p1x3vh1oiqKYFPmjdDJSdk4-nsonXnwVDFLMJCqc0GqY3C-h4XbfQNzxZP5-syrsQPI7izptZ-oMAKjJ6sRfP0YuMPmsJfQq_f-yzDHPSnqJPrJPh8mTANOy9QS-CMhm9Nhma0M78X58v_5RRk7H5U37jAcPeLd4mnAJEqAQVN3kJ8g5AS1MVStlfWqazkg</recordid><startdate>20160301</startdate><enddate>20160301</enddate><creator>Ferreira Galvao, F.H</creator><creator>Araki, J</creator><creator>Seid, V.E</creator><creator>Waisberg, D.R</creator><creator>Traldi, M.C</creator><creator>Naito, M</creator><creator>Araujo, B.C</creator><creator>Lanchotte, C</creator><creator>Chaib, E</creator><creator>D'Albuquerque, L.A.C</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20160301</creationdate><title>Evidence That Anorectal Transplantation Is the Logical Treatment for Serious Anorectal Dysfunction and Permanent Colostomy</title><author>Ferreira Galvao, F.H ; Araki, J ; Seid, V.E ; Waisberg, D.R ; Traldi, M.C ; Naito, M ; Araujo, B.C ; Lanchotte, C ; Chaib, E ; D'Albuquerque, L.A.C</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c435t-3b5ae6d3481e161ca0327ed3d931f947ddae31c8d08d789b4ae1c5618bdd5b03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Animals</topic><topic>Colostomy</topic><topic>Dogs</topic><topic>Fecal Incontinence - surgery</topic><topic>Humans</topic><topic>Quality of Life</topic><topic>Rats</topic><topic>Recovery of Function</topic><topic>Rectum - transplantation</topic><topic>Surgery</topic><topic>Swine</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ferreira Galvao, F.H</creatorcontrib><creatorcontrib>Araki, J</creatorcontrib><creatorcontrib>Seid, V.E</creatorcontrib><creatorcontrib>Waisberg, D.R</creatorcontrib><creatorcontrib>Traldi, M.C</creatorcontrib><creatorcontrib>Naito, M</creatorcontrib><creatorcontrib>Araujo, B.C</creatorcontrib><creatorcontrib>Lanchotte, C</creatorcontrib><creatorcontrib>Chaib, E</creatorcontrib><creatorcontrib>D'Albuquerque, L.A.C</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Transplantation proceedings</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ferreira Galvao, F.H</au><au>Araki, J</au><au>Seid, V.E</au><au>Waisberg, D.R</au><au>Traldi, M.C</au><au>Naito, M</au><au>Araujo, B.C</au><au>Lanchotte, C</au><au>Chaib, E</au><au>D'Albuquerque, L.A.C</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Evidence That Anorectal Transplantation Is the Logical Treatment for Serious Anorectal Dysfunction and Permanent Colostomy</atitle><jtitle>Transplantation proceedings</jtitle><addtitle>Transplant Proc</addtitle><date>2016-03-01</date><risdate>2016</risdate><volume>48</volume><issue>2</issue><spage>497</spage><epage>498</epage><pages>497-498</pages><issn>0041-1345</issn><eissn>1873-2623</eissn><abstract>Abstract Anorectal dysfunction resulting in fecal incontinence or permanent colostomy is a current public health concern that strongly impairs patient quality of life. 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| fulltext | fulltext |
| identifier | ISSN: 0041-1345 |
| ispartof | Transplantation proceedings, 2016-03, Vol.48 (2), p.497-498 |
| issn | 0041-1345 1873-2623 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Colostomy Dogs Fecal Incontinence - surgery Humans Quality of Life Rats Recovery of Function Rectum - transplantation Surgery Swine |
| title | Evidence That Anorectal Transplantation Is the Logical Treatment for Serious Anorectal Dysfunction and Permanent Colostomy |
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