Nickel, cobalt and chromium-induced cytotoxicity and intracellular accumulation in human hacat keratinocytes

Nickel, cobalt and chromium can induce allergic contact dermatitis (ACD) and may provoke irritant reactions in the skin. This study aimed at investigating cytotoxicity and cell viability along with intracellular metal accumulation in HaCaT human keratinocytes exposed to soluble forms of nickel, coba...

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Veröffentlicht in:	Toxicology (Amsterdam) 2001-02, Vol.159 (1), p.23-31
Hauptverfasser:	Ermolli, Monica, Menné, Charlotte, Pozzi, Giovanni, Serra, Miguel-Ángel, Clerici, Libero A
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell Line Cell Survival - drug effects Chemical and industrial products toxicology. Toxic occupational diseases Chromium Chromium - metabolism Chromium - toxicity Cobalt Cobalt - metabolism Cobalt - toxicity Colony-Forming Units Assay Cytotoxicity Human keratinocytes Humans Indicators and Reagents Keratinocytes - drug effects Keratinocytes - metabolism Medical sciences Metals and various inorganic compounds Nickel Nickel - metabolism Nickel - toxicity Nitroblue Tetrazolium Subcellular Fractions - drug effects Subcellular Fractions - metabolism Toxicology Uptake
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