Ectopic parathyroid adenoma presenting as facial expansile growths
Giant cell reparative granuloma of the facial skeleton is a rare presentation of hyperparathyroidism. A 17-year-old girl presented with progressive expansile bony growths of the mandible and maxilla. The case was investigated using biopsies, blood tests, imaging, and surgery. Biopsies confirmed gian...
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| Veröffentlicht in: | B-ENT (Leuven) 2016, Vol.12 (1), p.73-76 |
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| creator | Dhiwakar, M Damodharan, S Rajeshwari, K M Mehta, S |
| description | Giant cell reparative granuloma of the facial skeleton is a rare presentation of hyperparathyroidism.
A 17-year-old girl presented with progressive expansile bony growths of the mandible and maxilla. The case was investigated using biopsies, blood tests, imaging, and surgery.
Biopsies confirmed giant cell reparative granuloma. Blood testing revealed very high parathyroid hormone levels, and brown tumours due to primary hyperparathyroidism weresuspected. Surgical removal of an ectopic adenoma led to correction of the endocrine condition.
To our knowledge, this is the first reported case of multiple brown tumours of the facial skeleton due to an ectopic parathyroid adenoma. Diagnostic pitfalls and therapeutic challenges are described. |
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A 17-year-old girl presented with progressive expansile bony growths of the mandible and maxilla. The case was investigated using biopsies, blood tests, imaging, and surgery.
Biopsies confirmed giant cell reparative granuloma. Blood testing revealed very high parathyroid hormone levels, and brown tumours due to primary hyperparathyroidism weresuspected. Surgical removal of an ectopic adenoma led to correction of the endocrine condition.
To our knowledge, this is the first reported case of multiple brown tumours of the facial skeleton due to an ectopic parathyroid adenoma. Diagnostic pitfalls and therapeutic challenges are described.</description><identifier>ISSN: 1781-782X</identifier><identifier>PMID: 27097397</identifier><language>eng</language><publisher>Belgium</publisher><subject>Adenoma - complications ; Adenoma - diagnosis ; Adenoma - surgery ; Adolescent ; Choristoma - diagnosis ; Choristoma - surgery ; Female ; Granuloma, Giant Cell - diagnosis ; Granuloma, Giant Cell - etiology ; Humans ; Hyperparathyroidism, Primary - complications ; Hyperparathyroidism, Primary - diagnosis ; Hyperparathyroidism, Primary - surgery ; Magnetic Resonance Imaging ; Mandible - diagnostic imaging ; Mandible - pathology ; Maxilla - diagnostic imaging ; Maxilla - pathology ; Parathyroid Glands ; Parathyroid Neoplasms - complications ; Parathyroid Neoplasms - diagnosis ; Parathyroid Neoplasms - surgery ; Radionuclide Imaging ; Thyroid Diseases - diagnosis ; Thyroid Diseases - surgery ; Tomography, X-Ray Computed</subject><ispartof>B-ENT (Leuven), 2016, Vol.12 (1), p.73-76</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27097397$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dhiwakar, M</creatorcontrib><creatorcontrib>Damodharan, S</creatorcontrib><creatorcontrib>Rajeshwari, K M</creatorcontrib><creatorcontrib>Mehta, S</creatorcontrib><title>Ectopic parathyroid adenoma presenting as facial expansile growths</title><title>B-ENT (Leuven)</title><addtitle>B-ENT</addtitle><description>Giant cell reparative granuloma of the facial skeleton is a rare presentation of hyperparathyroidism.
A 17-year-old girl presented with progressive expansile bony growths of the mandible and maxilla. The case was investigated using biopsies, blood tests, imaging, and surgery.
Biopsies confirmed giant cell reparative granuloma. Blood testing revealed very high parathyroid hormone levels, and brown tumours due to primary hyperparathyroidism weresuspected. Surgical removal of an ectopic adenoma led to correction of the endocrine condition.
To our knowledge, this is the first reported case of multiple brown tumours of the facial skeleton due to an ectopic parathyroid adenoma. Diagnostic pitfalls and therapeutic challenges are described.</description><subject>Adenoma - complications</subject><subject>Adenoma - diagnosis</subject><subject>Adenoma - surgery</subject><subject>Adolescent</subject><subject>Choristoma - diagnosis</subject><subject>Choristoma - surgery</subject><subject>Female</subject><subject>Granuloma, Giant Cell - diagnosis</subject><subject>Granuloma, Giant Cell - etiology</subject><subject>Humans</subject><subject>Hyperparathyroidism, Primary - complications</subject><subject>Hyperparathyroidism, Primary - diagnosis</subject><subject>Hyperparathyroidism, Primary - surgery</subject><subject>Magnetic Resonance Imaging</subject><subject>Mandible - diagnostic imaging</subject><subject>Mandible - pathology</subject><subject>Maxilla - diagnostic imaging</subject><subject>Maxilla - pathology</subject><subject>Parathyroid Glands</subject><subject>Parathyroid Neoplasms - complications</subject><subject>Parathyroid Neoplasms - diagnosis</subject><subject>Parathyroid Neoplasms - surgery</subject><subject>Radionuclide Imaging</subject><subject>Thyroid Diseases - diagnosis</subject><subject>Thyroid Diseases - surgery</subject><subject>Tomography, X-Ray Computed</subject><issn>1781-782X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1j8tKAzEUQLNQbKn9BcnSzUBenZtZaqkPKLhRcDfcSe60kXnEZIr27y3Yrs7mcOBcsbkEKwuw6nPGljl_CSEkGCVKfcNmCkQFuoI5e9y4aYzB8YgJp_0xjcFz9DSMPfKYKNMwhWHHMfMWXcCO02_EIYeO-C6NP9M-37LrFrtMyzMX7ONp875-KbZvz6_rh20RlZRTUekGhCVoXSkMVWKlJAlEKz14aBqgErxcWWeFbUkZ4UA3rjFoSmOU9UYv2P1_N6bx-0B5qvuQHXUdDjQecn0a1pUSsLIn9e6sHpqefB1T6DEd68u3_gNHbFP-</recordid><startdate>2016</startdate><enddate>2016</enddate><creator>Dhiwakar, M</creator><creator>Damodharan, S</creator><creator>Rajeshwari, K M</creator><creator>Mehta, S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>2016</creationdate><title>Ectopic parathyroid adenoma presenting as facial expansile growths</title><author>Dhiwakar, M ; Damodharan, S ; Rajeshwari, K M ; Mehta, S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p211t-93b708e7fc604e90521e0aa81d7d7bb7e67d158c808fe240c73bcb4a464428d43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Adenoma - complications</topic><topic>Adenoma - diagnosis</topic><topic>Adenoma - surgery</topic><topic>Adolescent</topic><topic>Choristoma - diagnosis</topic><topic>Choristoma - surgery</topic><topic>Female</topic><topic>Granuloma, Giant Cell - diagnosis</topic><topic>Granuloma, Giant Cell - etiology</topic><topic>Humans</topic><topic>Hyperparathyroidism, Primary - complications</topic><topic>Hyperparathyroidism, Primary - diagnosis</topic><topic>Hyperparathyroidism, Primary - surgery</topic><topic>Magnetic Resonance Imaging</topic><topic>Mandible - diagnostic imaging</topic><topic>Mandible - pathology</topic><topic>Maxilla - diagnostic imaging</topic><topic>Maxilla - pathology</topic><topic>Parathyroid Glands</topic><topic>Parathyroid Neoplasms - complications</topic><topic>Parathyroid Neoplasms - diagnosis</topic><topic>Parathyroid Neoplasms - surgery</topic><topic>Radionuclide Imaging</topic><topic>Thyroid Diseases - diagnosis</topic><topic>Thyroid Diseases - surgery</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dhiwakar, M</creatorcontrib><creatorcontrib>Damodharan, S</creatorcontrib><creatorcontrib>Rajeshwari, K M</creatorcontrib><creatorcontrib>Mehta, S</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>B-ENT (Leuven)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dhiwakar, M</au><au>Damodharan, S</au><au>Rajeshwari, K M</au><au>Mehta, S</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ectopic parathyroid adenoma presenting as facial expansile growths</atitle><jtitle>B-ENT (Leuven)</jtitle><addtitle>B-ENT</addtitle><date>2016</date><risdate>2016</risdate><volume>12</volume><issue>1</issue><spage>73</spage><epage>76</epage><pages>73-76</pages><issn>1781-782X</issn><abstract>Giant cell reparative granuloma of the facial skeleton is a rare presentation of hyperparathyroidism.
A 17-year-old girl presented with progressive expansile bony growths of the mandible and maxilla. The case was investigated using biopsies, blood tests, imaging, and surgery.
Biopsies confirmed giant cell reparative granuloma. Blood testing revealed very high parathyroid hormone levels, and brown tumours due to primary hyperparathyroidism weresuspected. Surgical removal of an ectopic adenoma led to correction of the endocrine condition.
To our knowledge, this is the first reported case of multiple brown tumours of the facial skeleton due to an ectopic parathyroid adenoma. Diagnostic pitfalls and therapeutic challenges are described.</abstract><cop>Belgium</cop><pmid>27097397</pmid><tpages>4</tpages></addata></record> |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adenoma - complications Adenoma - diagnosis Adenoma - surgery Adolescent Choristoma - diagnosis Choristoma - surgery Female Granuloma, Giant Cell - diagnosis Granuloma, Giant Cell - etiology Humans Hyperparathyroidism, Primary - complications Hyperparathyroidism, Primary - diagnosis Hyperparathyroidism, Primary - surgery Magnetic Resonance Imaging Mandible - diagnostic imaging Mandible - pathology Maxilla - diagnostic imaging Maxilla - pathology Parathyroid Glands Parathyroid Neoplasms - complications Parathyroid Neoplasms - diagnosis Parathyroid Neoplasms - surgery Radionuclide Imaging Thyroid Diseases - diagnosis Thyroid Diseases - surgery Tomography, X-Ray Computed |
| title | Ectopic parathyroid adenoma presenting as facial expansile growths |
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