Curcumin Attenuates Inflammation, Oxidative Stress, and Ultrastructural Damage Induced by Spinal Cord Ischemia–Reperfusion Injury in Rats

Objectives Curcumin is a molecule found in turmeric root that possesses anti-inflammatory and antioxidant properties and has been widely used to treat neurodegenerative diseases. We investigated whether curcumin stimulates the neurorepair process and improves locomotor function in a rat model of spi...

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Veröffentlicht in:	Journal of stroke and cerebrovascular diseases 2016-05, Vol.25 (5), p.1196-1207
Hauptverfasser:	Gokce, Emre Cemal, MD, Kahveci, Ramazan, MD, Gokce, Aysun, MD, Sargon, Mustafa Fevzi, MD, PhD, Kisa, Ucler, MD, Aksoy, Nurkan, MD, Cemil, Berker, MD, Erdogan, Bulent, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-Inflammatory Agents - pharmacology Antioxidants - pharmacology Apoptosis - drug effects Biomarkers - metabolism Cardiovascular Curcumin Curcumin - pharmacology Cytoprotection Disease Models, Animal inflammation Inflammation Mediators - metabolism lipid peroxidation Lipid Peroxidation - drug effects Locomotion - drug effects Male Motor Activity - drug effects Neurology Neuroprotective Agents - pharmacology oxidative stress Oxidative Stress - drug effects Rats, Wistar Reperfusion Injury - metabolism Reperfusion Injury - pathology Reperfusion Injury - physiopathology Reperfusion Injury - prevention & control Spinal Cord - drug effects Spinal Cord - metabolism Spinal Cord - physiopathology Spinal Cord - ultrastructure Spinal Cord Ischemia - drug therapy Spinal Cord Ischemia - metabolism Spinal Cord Ischemia - pathology Spinal Cord Ischemia - physiopathology spinal cord ischemia–reperfusion injury Time Factors
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