Prenatal and Postnatal Survival of Fetal Tetralogy of Fallot: A Meta-analysis of Perinatal Outcomes and Associated Genetic Disorders
The aim of this systematic review was to compare the postnatal outcomes, genetic testing results, and sonographic findings in 3 subtypes of tetralogy of Fallot. Thirty-six articles from the MEDLINE and EMBASE databases were selected for this review. The postnatal outcomes, karyotyping results, and s...
Gespeichert in:
| Veröffentlicht in: | Journal of ultrasound in medicine 2016-05, Vol.35 (5), p.905-915 |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 915 |
|---|---|
| container_issue | 5 |
| container_start_page | 905 |
| container_title | Journal of ultrasound in medicine |
| container_volume | 35 |
| creator | Zhao, Yili Abuhamad, Alfred Fleenor, Jonathan Guo, Yajun Zhang, Wangshu Cao, Danming Zeng, Shi Sinkovskaya, Elena Zhou, Qichang |
| description | The aim of this systematic review was to compare the postnatal outcomes, genetic testing results, and sonographic findings in 3 subtypes of tetralogy of Fallot.
Thirty-six articles from the MEDLINE and EMBASE databases were selected for this review. The postnatal outcomes, karyotyping results, and sonographic findings of fetal tetralogy of Fallot with pulmonary stenosis, tetralogy of Fallot with pulmonary atresia, and tetralogy of Fallot with an absent pulmonary valve were collected and compared.
The survival rates (termination of pregnancy was considered fetal death) for prenatally diagnosed tetralogy of Fallot with pulmonary atresia and tetralogy of Fallot with an absent pulmonary valve at the end of neonatal period were significantly lower than the rate for tetralogy of Fallot with pulmonary stenosis (P < .05). The survival rate for tetralogy of Fallot with pulmonary atresia was also lower at birth (P < .001). Major chromosomal anomalies were more frequently detected in tetralogy of Fallot with pulmonary stenosis (P< .05); conversely, 22q11 deletion was present more often in fetuses with tetralogy of Fallot with pulmonary atresia and tetralogy of Fallot with an absent pulmonary valve (P < .001). Compared to tetralogy of Fallot with pulmonary stenosis, a right aortic arch was more associated with tetralogy of Fallot with pulmonary atresia (32.6%; P < .05), and the ductus arteriosus was almost always absent in tetralogy of Fallot with an absent pulmonary valve (87.5%; P < .001).
The postnatal outcomes, genetic testing results, and sonographic findings are different among subtypes of tetralogy of Fallot. Documenting those details at diagnosis can help specialists better counsel their patients. |
| doi_str_mv | 10.7863/ultra.15.04055 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1783912907</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1783912907</sourcerecordid><originalsourceid>FETCH-LOGICAL-c250t-85dc3cea836498e27164612ad9266eabab142ac02294ca89cdd4b068c9ade2513</originalsourceid><addsrcrecordid>eNo9UD1PwzAQtRAISmFlRBlZUmwnjmO2im-pqJUoc3SxryjIjcF2KnXnh5M2wHR37717p3uEXDA6kWWRXXc2epgwMaE5FeKAjJgQNFUFyw7JiHJZpjlX8oSchvBBKadM5sfkhEvKOZN8RL4XHluIYBNoTbJwIQ7Ta-c3zaZv3Cp5wB2yxP6Sde_bPQTWuniTTJOXnkyhBbsNTdhRC_TN4DHvonZrDHvraQhONxDRJI_YYmx0ctcE5w36cEaOVmADnv_WMXl7uF_ePqWz-ePz7XSWai5oTEthdKYRyqzIVYlcsiIvGAejeFEg1FCznIPuX1O5hlJpY_KaFqVWYJALlo3J1eD76d1XhyFW6yZotBZadF2omCwzxbiispdOBqn2LgSPq-rTN2vw24rRapd8tU--YqLaJ98vXP56d_Uazb_8L-rsB-EMgVA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1783912907</pqid></control><display><type>article</type><title>Prenatal and Postnatal Survival of Fetal Tetralogy of Fallot: A Meta-analysis of Perinatal Outcomes and Associated Genetic Disorders</title><source>MEDLINE</source><source>Wiley Online Library All Journals</source><creator>Zhao, Yili ; Abuhamad, Alfred ; Fleenor, Jonathan ; Guo, Yajun ; Zhang, Wangshu ; Cao, Danming ; Zeng, Shi ; Sinkovskaya, Elena ; Zhou, Qichang</creator><creatorcontrib>Zhao, Yili ; Abuhamad, Alfred ; Fleenor, Jonathan ; Guo, Yajun ; Zhang, Wangshu ; Cao, Danming ; Zeng, Shi ; Sinkovskaya, Elena ; Zhou, Qichang</creatorcontrib><description><![CDATA[The aim of this systematic review was to compare the postnatal outcomes, genetic testing results, and sonographic findings in 3 subtypes of tetralogy of Fallot.
Thirty-six articles from the MEDLINE and EMBASE databases were selected for this review. The postnatal outcomes, karyotyping results, and sonographic findings of fetal tetralogy of Fallot with pulmonary stenosis, tetralogy of Fallot with pulmonary atresia, and tetralogy of Fallot with an absent pulmonary valve were collected and compared.
The survival rates (termination of pregnancy was considered fetal death) for prenatally diagnosed tetralogy of Fallot with pulmonary atresia and tetralogy of Fallot with an absent pulmonary valve at the end of neonatal period were significantly lower than the rate for tetralogy of Fallot with pulmonary stenosis (P < .05). The survival rate for tetralogy of Fallot with pulmonary atresia was also lower at birth (P < .001). Major chromosomal anomalies were more frequently detected in tetralogy of Fallot with pulmonary stenosis (P< .05); conversely, 22q11 deletion was present more often in fetuses with tetralogy of Fallot with pulmonary atresia and tetralogy of Fallot with an absent pulmonary valve (P < .001). Compared to tetralogy of Fallot with pulmonary stenosis, a right aortic arch was more associated with tetralogy of Fallot with pulmonary atresia (32.6%; P < .05), and the ductus arteriosus was almost always absent in tetralogy of Fallot with an absent pulmonary valve (87.5%; P < .001).
The postnatal outcomes, genetic testing results, and sonographic findings are different among subtypes of tetralogy of Fallot. Documenting those details at diagnosis can help specialists better counsel their patients.]]></description><identifier>ISSN: 0278-4297</identifier><identifier>EISSN: 1550-9613</identifier><identifier>DOI: 10.7863/ultra.15.04055</identifier><identifier>PMID: 27022172</identifier><language>eng</language><publisher>England</publisher><subject>Female ; Genetic Testing - statistics & numerical data ; Humans ; Pregnancy ; Pregnancy Outcome - epidemiology ; Survival Analysis ; Tetralogy of Fallot - diagnostic imaging ; Tetralogy of Fallot - epidemiology ; Ultrasonography, Prenatal - methods</subject><ispartof>Journal of ultrasound in medicine, 2016-05, Vol.35 (5), p.905-915</ispartof><rights>2016 by the American Institute of Ultrasound in Medicine.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c250t-85dc3cea836498e27164612ad9266eabab142ac02294ca89cdd4b068c9ade2513</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/27022172$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Zhao, Yili</creatorcontrib><creatorcontrib>Abuhamad, Alfred</creatorcontrib><creatorcontrib>Fleenor, Jonathan</creatorcontrib><creatorcontrib>Guo, Yajun</creatorcontrib><creatorcontrib>Zhang, Wangshu</creatorcontrib><creatorcontrib>Cao, Danming</creatorcontrib><creatorcontrib>Zeng, Shi</creatorcontrib><creatorcontrib>Sinkovskaya, Elena</creatorcontrib><creatorcontrib>Zhou, Qichang</creatorcontrib><title>Prenatal and Postnatal Survival of Fetal Tetralogy of Fallot: A Meta-analysis of Perinatal Outcomes and Associated Genetic Disorders</title><title>Journal of ultrasound in medicine</title><addtitle>J Ultrasound Med</addtitle><description><![CDATA[The aim of this systematic review was to compare the postnatal outcomes, genetic testing results, and sonographic findings in 3 subtypes of tetralogy of Fallot.
Thirty-six articles from the MEDLINE and EMBASE databases were selected for this review. The postnatal outcomes, karyotyping results, and sonographic findings of fetal tetralogy of Fallot with pulmonary stenosis, tetralogy of Fallot with pulmonary atresia, and tetralogy of Fallot with an absent pulmonary valve were collected and compared.
The survival rates (termination of pregnancy was considered fetal death) for prenatally diagnosed tetralogy of Fallot with pulmonary atresia and tetralogy of Fallot with an absent pulmonary valve at the end of neonatal period were significantly lower than the rate for tetralogy of Fallot with pulmonary stenosis (P < .05). The survival rate for tetralogy of Fallot with pulmonary atresia was also lower at birth (P < .001). Major chromosomal anomalies were more frequently detected in tetralogy of Fallot with pulmonary stenosis (P< .05); conversely, 22q11 deletion was present more often in fetuses with tetralogy of Fallot with pulmonary atresia and tetralogy of Fallot with an absent pulmonary valve (P < .001). Compared to tetralogy of Fallot with pulmonary stenosis, a right aortic arch was more associated with tetralogy of Fallot with pulmonary atresia (32.6%; P < .05), and the ductus arteriosus was almost always absent in tetralogy of Fallot with an absent pulmonary valve (87.5%; P < .001).
The postnatal outcomes, genetic testing results, and sonographic findings are different among subtypes of tetralogy of Fallot. Documenting those details at diagnosis can help specialists better counsel their patients.]]></description><subject>Female</subject><subject>Genetic Testing - statistics & numerical data</subject><subject>Humans</subject><subject>Pregnancy</subject><subject>Pregnancy Outcome - epidemiology</subject><subject>Survival Analysis</subject><subject>Tetralogy of Fallot - diagnostic imaging</subject><subject>Tetralogy of Fallot - epidemiology</subject><subject>Ultrasonography, Prenatal - methods</subject><issn>0278-4297</issn><issn>1550-9613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2016</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9UD1PwzAQtRAISmFlRBlZUmwnjmO2im-pqJUoc3SxryjIjcF2KnXnh5M2wHR37717p3uEXDA6kWWRXXc2epgwMaE5FeKAjJgQNFUFyw7JiHJZpjlX8oSchvBBKadM5sfkhEvKOZN8RL4XHluIYBNoTbJwIQ7Ta-c3zaZv3Cp5wB2yxP6Sde_bPQTWuniTTJOXnkyhBbsNTdhRC_TN4DHvonZrDHvraQhONxDRJI_YYmx0ctcE5w36cEaOVmADnv_WMXl7uF_ePqWz-ePz7XSWai5oTEthdKYRyqzIVYlcsiIvGAejeFEg1FCznIPuX1O5hlJpY_KaFqVWYJALlo3J1eD76d1XhyFW6yZotBZadF2omCwzxbiispdOBqn2LgSPq-rTN2vw24rRapd8tU--YqLaJ98vXP56d_Uazb_8L-rsB-EMgVA</recordid><startdate>201605</startdate><enddate>201605</enddate><creator>Zhao, Yili</creator><creator>Abuhamad, Alfred</creator><creator>Fleenor, Jonathan</creator><creator>Guo, Yajun</creator><creator>Zhang, Wangshu</creator><creator>Cao, Danming</creator><creator>Zeng, Shi</creator><creator>Sinkovskaya, Elena</creator><creator>Zhou, Qichang</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201605</creationdate><title>Prenatal and Postnatal Survival of Fetal Tetralogy of Fallot: A Meta-analysis of Perinatal Outcomes and Associated Genetic Disorders</title><author>Zhao, Yili ; Abuhamad, Alfred ; Fleenor, Jonathan ; Guo, Yajun ; Zhang, Wangshu ; Cao, Danming ; Zeng, Shi ; Sinkovskaya, Elena ; Zhou, Qichang</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c250t-85dc3cea836498e27164612ad9266eabab142ac02294ca89cdd4b068c9ade2513</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2016</creationdate><topic>Female</topic><topic>Genetic Testing - statistics & numerical data</topic><topic>Humans</topic><topic>Pregnancy</topic><topic>Pregnancy Outcome - epidemiology</topic><topic>Survival Analysis</topic><topic>Tetralogy of Fallot - diagnostic imaging</topic><topic>Tetralogy of Fallot - epidemiology</topic><topic>Ultrasonography, Prenatal - methods</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Zhao, Yili</creatorcontrib><creatorcontrib>Abuhamad, Alfred</creatorcontrib><creatorcontrib>Fleenor, Jonathan</creatorcontrib><creatorcontrib>Guo, Yajun</creatorcontrib><creatorcontrib>Zhang, Wangshu</creatorcontrib><creatorcontrib>Cao, Danming</creatorcontrib><creatorcontrib>Zeng, Shi</creatorcontrib><creatorcontrib>Sinkovskaya, Elena</creatorcontrib><creatorcontrib>Zhou, Qichang</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of ultrasound in medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Zhao, Yili</au><au>Abuhamad, Alfred</au><au>Fleenor, Jonathan</au><au>Guo, Yajun</au><au>Zhang, Wangshu</au><au>Cao, Danming</au><au>Zeng, Shi</au><au>Sinkovskaya, Elena</au><au>Zhou, Qichang</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prenatal and Postnatal Survival of Fetal Tetralogy of Fallot: A Meta-analysis of Perinatal Outcomes and Associated Genetic Disorders</atitle><jtitle>Journal of ultrasound in medicine</jtitle><addtitle>J Ultrasound Med</addtitle><date>2016-05</date><risdate>2016</risdate><volume>35</volume><issue>5</issue><spage>905</spage><epage>915</epage><pages>905-915</pages><issn>0278-4297</issn><eissn>1550-9613</eissn><abstract><![CDATA[The aim of this systematic review was to compare the postnatal outcomes, genetic testing results, and sonographic findings in 3 subtypes of tetralogy of Fallot.
Thirty-six articles from the MEDLINE and EMBASE databases were selected for this review. The postnatal outcomes, karyotyping results, and sonographic findings of fetal tetralogy of Fallot with pulmonary stenosis, tetralogy of Fallot with pulmonary atresia, and tetralogy of Fallot with an absent pulmonary valve were collected and compared.
The survival rates (termination of pregnancy was considered fetal death) for prenatally diagnosed tetralogy of Fallot with pulmonary atresia and tetralogy of Fallot with an absent pulmonary valve at the end of neonatal period were significantly lower than the rate for tetralogy of Fallot with pulmonary stenosis (P < .05). The survival rate for tetralogy of Fallot with pulmonary atresia was also lower at birth (P < .001). Major chromosomal anomalies were more frequently detected in tetralogy of Fallot with pulmonary stenosis (P< .05); conversely, 22q11 deletion was present more often in fetuses with tetralogy of Fallot with pulmonary atresia and tetralogy of Fallot with an absent pulmonary valve (P < .001). Compared to tetralogy of Fallot with pulmonary stenosis, a right aortic arch was more associated with tetralogy of Fallot with pulmonary atresia (32.6%; P < .05), and the ductus arteriosus was almost always absent in tetralogy of Fallot with an absent pulmonary valve (87.5%; P < .001).
The postnatal outcomes, genetic testing results, and sonographic findings are different among subtypes of tetralogy of Fallot. Documenting those details at diagnosis can help specialists better counsel their patients.]]></abstract><cop>England</cop><pmid>27022172</pmid><doi>10.7863/ultra.15.04055</doi><tpages>11</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0278-4297 |
| ispartof | Journal of ultrasound in medicine, 2016-05, Vol.35 (5), p.905-915 |
| issn | 0278-4297 1550-9613 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_1783912907 |
| source | MEDLINE; Wiley Online Library All Journals |
| subjects | Female Genetic Testing - statistics & numerical data Humans Pregnancy Pregnancy Outcome - epidemiology Survival Analysis Tetralogy of Fallot - diagnostic imaging Tetralogy of Fallot - epidemiology Ultrasonography, Prenatal - methods |
| title | Prenatal and Postnatal Survival of Fetal Tetralogy of Fallot: A Meta-analysis of Perinatal Outcomes and Associated Genetic Disorders |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-12T01%3A36%3A05IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prenatal%20and%20Postnatal%20Survival%20of%20Fetal%20Tetralogy%20of%20Fallot:%20A%20Meta-analysis%20of%20Perinatal%20Outcomes%20and%20Associated%20Genetic%20Disorders&rft.jtitle=Journal%20of%20ultrasound%20in%20medicine&rft.au=Zhao,%20Yili&rft.date=2016-05&rft.volume=35&rft.issue=5&rft.spage=905&rft.epage=915&rft.pages=905-915&rft.issn=0278-4297&rft.eissn=1550-9613&rft_id=info:doi/10.7863/ultra.15.04055&rft_dat=%3Cproquest_cross%3E1783912907%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1783912907&rft_id=info:pmid/27022172&rfr_iscdi=true |