Anaphylaxis to excipient mannitol: evidence for an immunoglobulin E-mediated mechanism

Summary Background Anaphylaxis to mannitol present naturally in pomegranate and cultivated mushroom in a sensitized subject has been described recently, and an IgE‐mediated mechanism to this sugar alcohol has been proposed. The same subject also experienced severe allergic reactions to a chewable ph...

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Veröffentlicht in:	Clinical and experimental allergy 2004-10, Vol.34 (10), p.1602-1609
Hauptverfasser:	Hegde, V. L., Venkatesh, Y. P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult alditol-protein conjugates Allergens - immunology Allergic diseases anaphylaxis Anaphylaxis - blood Anaphylaxis - immunology Biological and medical sciences chemical allergy Chromatography, High Pressure Liquid - methods cisapride Cisapride - adverse effects Cisapride - immunology Enzyme-Linked Immunosorbent Assay - methods excipient Excipients - adverse effects Female food additive Food Additives - adverse effects Food Hypersensitivity - blood Food Hypersensitivity - immunology Fundamental and applied biological sciences. Psychology Fundamental immunology hapten Humans Immunoglobulin E - blood Immunoglobulin E - immunology Immunopathology mannitol Mannitol - adverse effects Mannitol - immunology mannitol-BSA mannitol-specific IgE Medical sciences Punicaceae - adverse effects Punicaceae - immunology Skin Tests - methods Sorbitol - immunology Sugar Alcohols - immunology
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