Mineral density and histomorphometric assessment of bone changes in the proximal tibia early after induction of type II collagen-induced arthritis in growing and mature rats

Bone changes in both actively growing (6-week-old) and mature (6-month-old) rats with collagen-induced arthritis (CIA) were investigated in order to clarify the mechanisms of osteoporosis near inflamed joints in patients with early rheumatoid arthritis (RA) and juvenile RA. In female Sprague-Dawley...

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Veröffentlicht in:	Journal of bone and mineral metabolism 2001-01, Vol.19 (2), p.76-83
Hauptverfasser:	HOSHINO, Ken-Ichi, HANYU, Tadamasa, ARAI, Katsumitsu, TAKAHASHI, Hideaki E
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arthritis, Rheumatoid - chemically induced Arthritis, Rheumatoid - diagnostic imaging Arthritis, Rheumatoid - pathology Arthritis, Rheumatoid - physiopathology Biological and medical sciences Bone Density Bones Collagen - adverse effects Disease Models, Animal Diseases of the osteoarticular system Female Immunization Inflammatory joint diseases Medical sciences Radiography Rats Rats, Sprague-Dawley Rodents Tibia - diagnostic imaging Tibia - pathology Tibia - physiopathology
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