Demonstration of a functional motilin receptor in TE671 cells from human cerebellum

Background: Our laboratory has described the presence of motilin receptors in the rabbit cerebellum. We discovered its presence in the human TE671 cell line, which is of cerebellar origin. Methods: Cytosolic Ca 2+ fluxes were monitored on a confocal microscope in cells loaded with Indo-1 and stimula...

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Veröffentlicht in:	Brain research 2001-03, Vol.895 (1), p.119-128
Hauptverfasser:	Thielemans, Leen, Depoortere, Inge, Van Assche, Gert, Bender, Eckhard, Peeters, Theo L
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Calcium signaling Calcium Signaling - drug effects Calcium Signaling - physiology Cell receptors Cell structures and functions Cerebellum - cytology Cerebellum - drug effects Cerebellum - metabolism DNA, Complementary - metabolism Dose-Response Relationship, Drug Drug Interactions - physiology Fundamental and applied biological sciences. Psychology Humans Iodine Radioisotopes - pharmacology Medulloblastoma Miscellaneous Molecular and cellular biology Motilin - agonists Motilin - antagonists & inhibitors Motilin - metabolism Motilin receptor motilin receptors Neurons - cytology Neurons - drug effects Neurons - metabolism Norleucine - pharmacology Radioligand Assay Receptors, Gastrointestinal Hormone - drug effects Receptors, Gastrointestinal Hormone - metabolism Receptors, Neuropeptide - drug effects Receptors, Neuropeptide - metabolism Signal Transduction - drug effects Signal Transduction - physiology Tachyphylaxis - physiology Tumor Cells, Cultured - cytology Tumor Cells, Cultured - drug effects Tumor Cells, Cultured - metabolism
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