PAN1/NALP2/PYPAF2, an Inducible Inflammatory Mediator That Regulates NF-κB and Caspase-1 Activation in Macrophages

Genes encoding proteins with PYRIN/PAAD/DAPIN domains, a nucleotide binding fold (NACHT), and leucine rich repeats have recently been recognized as important mediators in autoimmune inflammatory disorders. Here we characterize the expression and function of a member of the PYRIN and NACHT domain (PA...

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Veröffentlicht in:	The Journal of biological chemistry 2004-12, Vol.279 (50), p.51897-51907
Hauptverfasser:	Bruey, Jean Marie, Bruey-Sedano, Nathalie, Newman, Ruchi, Chandler, Sharon, Stehlik, Christian, Reed, John C.
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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