Myomir dysregulation and reactive oxygen species in aged human satellite cells

Satellite cells that reside on the myofibre surface are crucial for the muscle homeostasis and regeneration. Aging goes along with a less effective regeneration of skeletal muscle tissue mainly due to the decreased myogenic capability of satellite cells. This phenomenon impedes proper maintenance an...

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Veröffentlicht in:	Biochemical and biophysical research communications 2016-04, Vol.473 (2), p.462-470
Hauptverfasser:	Di Filippo, Ester Sara, Mancinelli, Rosa, Pietrangelo, Tiziana, La Rovere, Rita Maria Laura, Quattrocelli, Mattia, Sampaolesi, Maurilio, Fulle, Stefania
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Aging Cells, Cultured Gene Expression Regulation Human satellite cells Humans Male MicroRNAs - genetics Muscle Development myomiRNAs Reactive Oxygen Species - metabolism ROS Sarcopenia Sarcopenia - genetics Sarcopenia - metabolism Satellite Cells, Skeletal Muscle - cytology Satellite Cells, Skeletal Muscle - metabolism Young Adult
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