TAG-1-Deficient Mice Have Marked Elevation of Adenosine A1 Receptors in the Hippocampus

TAG-1 is a neural recognition molecule in the immunoglobulin superfamily that is predominantly expressed in the developing brain. Several lines of evidence suggest that TAG-1 is involved in the outgrowth, guidance, and fasciculation of neurites. To directly assess the function of TAG-1 in vivo, we h...

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Veröffentlicht in:	Biochemical and biophysical research communications 2001-02, Vol.281 (1), p.220-226
Hauptverfasser:	Fukamauchi, Fumihiko, Aihara, Okihiko, Wang, Yi-Jun, Akasaka, Keiko, Takeda, Yasuo, Horie, Masao, Kawano, Hitoshi, Sudo, Katsuko, Asano, Masahide, Watanabe, Kazutada, Iwakura, Yoichiro
Format:	Artikel
Sprache:	eng
Schlagworte:	adenosine receptor Animals Antibodies - metabolism Blotting, Southern Blotting, Western Cell Adhesion Cell Adhesion Molecules, Neuronal Cerebellum - metabolism Contactin 2 Embryo, Mammalian - metabolism Gene Deletion gene targeting Hippocampus - metabolism hippocampus, convulsive behavior immunoglobulin superfamily Immunohistochemistry Membrane Glycoproteins - genetics Membrane Glycoproteins - physiology Mice Mice, Knockout Models, Genetic Mutagenesis, Site-Directed Rabbits Receptors, Purinergic P1 - biosynthesis Recombination, Genetic Seizures - genetics Spinal Cord - metabolism Stem Cells - metabolism TAG-1 Up-Regulation
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