Gas chromatographic separation of R/ S-α-hydroxy fatty acid esters
Gas chromatographic (GC) separations of R/ S-α-hydroxy fatty acids (AHFAs) are carried out on several columns, including α-cyclodextrin derivative (CYDEX-B) chiral column. R/ S-AHFAs are well separated on achiral columns (BP-1, non-polar phase and Rtx-2330, very polar phase) as diasteriomeric esters...
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| Veröffentlicht in: | Analytica Chimica Acta 2002-08, Vol.465 (1), p.299-307 |
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| container_title | Analytica Chimica Acta |
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| creator | Tokamolthom, Jindarat Chen, Shui-Tein Jeyashoke, Narumon Krisnangkura, Kanit |
| description | Gas chromatographic (GC) separations of
R/
S-α-hydroxy fatty acids (AHFAs) are carried out on several columns, including α-cyclodextrin derivative (CYDEX-B) chiral column.
R/
S-AHFAs are well separated on achiral columns (BP-1, non-polar phase and Rtx-2330, very polar phase) as diasteriomeric esters of the optically active alcohols, whereas the shorter chain length of the alcohol tends to give lower separation factor (
α) on the same column. The longest chain length of alcohol used in this study is 2-octanol and its ester shows the highest α on the Rtx-2330 capillary column.
Thus, the four thermodynamically related column constants (
a,
b,
c and
d) of
Eq. (1) for
R- and
S-AHFAs standard are determined.
ln
k′=a+bn+
c
T
+
dn
T
where
k′ is the retention factor,
n the equivalent carbon number and
T the absolute temperature. This equation is used to estimate the equivalent
n, and also subsequently used to identify and determine the configuration of AHFAs in wool wax without using a standard AHFA as a reference. |
| doi_str_mv | 10.1016/S0003-2670(02)00400-2 |
| format | Article |
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R/
S-α-hydroxy fatty acids (AHFAs) are carried out on several columns, including α-cyclodextrin derivative (CYDEX-B) chiral column.
R/
S-AHFAs are well separated on achiral columns (BP-1, non-polar phase and Rtx-2330, very polar phase) as diasteriomeric esters of the optically active alcohols, whereas the shorter chain length of the alcohol tends to give lower separation factor (
α) on the same column. The longest chain length of alcohol used in this study is 2-octanol and its ester shows the highest α on the Rtx-2330 capillary column.
Thus, the four thermodynamically related column constants (
a,
b,
c and
d) of
Eq. (1) for
R- and
S-AHFAs standard are determined.
ln
k′=a+bn+
c
T
+
dn
T
where
k′ is the retention factor,
n the equivalent carbon number and
T the absolute temperature. This equation is used to estimate the equivalent
n, and also subsequently used to identify and determine the configuration of AHFAs in wool wax without using a standard AHFA as a reference.</description><identifier>ISSN: 0003-2670</identifier><identifier>EISSN: 1873-4324</identifier><identifier>DOI: 10.1016/S0003-2670(02)00400-2</identifier><language>eng</language><publisher>Elsevier B.V</publisher><subject>Diasteriomer ; Enantiomer ; Gas chromatography ; Hydroxy acid ester ; Resolution</subject><ispartof>Analytica Chimica Acta, 2002-08, Vol.465 (1), p.299-307</ispartof><rights>2002 Elsevier Science B.V.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c338t-980f6422f07185048e38ff7b550e3807a2758e2eb14a68fbf16891198e9407ed3</citedby><cites>FETCH-LOGICAL-c338t-980f6422f07185048e38ff7b550e3807a2758e2eb14a68fbf16891198e9407ed3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/S0003-2670(02)00400-2$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,315,781,785,793,3551,27927,27929,27930,46000</link.rule.ids></links><search><creatorcontrib>Tokamolthom, Jindarat</creatorcontrib><creatorcontrib>Chen, Shui-Tein</creatorcontrib><creatorcontrib>Jeyashoke, Narumon</creatorcontrib><creatorcontrib>Krisnangkura, Kanit</creatorcontrib><title>Gas chromatographic separation of R/ S-α-hydroxy fatty acid esters</title><title>Analytica Chimica Acta</title><description>Gas chromatographic (GC) separations of
R/
S-α-hydroxy fatty acids (AHFAs) are carried out on several columns, including α-cyclodextrin derivative (CYDEX-B) chiral column.
R/
S-AHFAs are well separated on achiral columns (BP-1, non-polar phase and Rtx-2330, very polar phase) as diasteriomeric esters of the optically active alcohols, whereas the shorter chain length of the alcohol tends to give lower separation factor (
α) on the same column. The longest chain length of alcohol used in this study is 2-octanol and its ester shows the highest α on the Rtx-2330 capillary column.
Thus, the four thermodynamically related column constants (
a,
b,
c and
d) of
Eq. (1) for
R- and
S-AHFAs standard are determined.
ln
k′=a+bn+
c
T
+
dn
T
where
k′ is the retention factor,
n the equivalent carbon number and
T the absolute temperature. This equation is used to estimate the equivalent
n, and also subsequently used to identify and determine the configuration of AHFAs in wool wax without using a standard AHFA as a reference.</description><subject>Diasteriomer</subject><subject>Enantiomer</subject><subject>Gas chromatography</subject><subject>Hydroxy acid ester</subject><subject>Resolution</subject><issn>0003-2670</issn><issn>1873-4324</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><recordid>eNqFkN1KAzEQhYMoWKuPIOyV6MXayc9uslciRatQEKxehzQ7sZG2WZNV3MfyRXwmt61469XMwDlnOB8hpxQuKdByNAMAnrNSwjmwCwABkLM9MqBK8lxwJvbJ4E9ySI5Seu1PRkEMyHhiUmYXMaxMG16iaRbeZgkbE03rwzoLLnscZbP8-ytfdHUMn13mTNt2mbG-zjC1GNMxOXBmmfDkdw7J8-3N0_gunz5M7sfX09xyrtq8UuBKwZgDSVUBQiFXzsl5UUC_gTRMFgoZzqkwpXJzR0tVUVoprARIrPmQnO1ymxje3vvfeuWTxeXSrDG8J02lorJkvBcWO6GNIaWITjfRr0zsNAW9Qaa3yPSGhwamt8g0631XOx_2LT48Rp2sx7XF2ke0ra6D_yfhB3gFcdM</recordid><startdate>20020816</startdate><enddate>20020816</enddate><creator>Tokamolthom, Jindarat</creator><creator>Chen, Shui-Tein</creator><creator>Jeyashoke, Narumon</creator><creator>Krisnangkura, Kanit</creator><general>Elsevier B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20020816</creationdate><title>Gas chromatographic separation of R/ S-α-hydroxy fatty acid esters</title><author>Tokamolthom, Jindarat ; Chen, Shui-Tein ; Jeyashoke, Narumon ; Krisnangkura, Kanit</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c338t-980f6422f07185048e38ff7b550e3807a2758e2eb14a68fbf16891198e9407ed3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Diasteriomer</topic><topic>Enantiomer</topic><topic>Gas chromatography</topic><topic>Hydroxy acid ester</topic><topic>Resolution</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tokamolthom, Jindarat</creatorcontrib><creatorcontrib>Chen, Shui-Tein</creatorcontrib><creatorcontrib>Jeyashoke, Narumon</creatorcontrib><creatorcontrib>Krisnangkura, Kanit</creatorcontrib><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Analytica Chimica Acta</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tokamolthom, Jindarat</au><au>Chen, Shui-Tein</au><au>Jeyashoke, Narumon</au><au>Krisnangkura, Kanit</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gas chromatographic separation of R/ S-α-hydroxy fatty acid esters</atitle><jtitle>Analytica Chimica Acta</jtitle><date>2002-08-16</date><risdate>2002</risdate><volume>465</volume><issue>1</issue><spage>299</spage><epage>307</epage><pages>299-307</pages><issn>0003-2670</issn><eissn>1873-4324</eissn><abstract>Gas chromatographic (GC) separations of
R/
S-α-hydroxy fatty acids (AHFAs) are carried out on several columns, including α-cyclodextrin derivative (CYDEX-B) chiral column.
R/
S-AHFAs are well separated on achiral columns (BP-1, non-polar phase and Rtx-2330, very polar phase) as diasteriomeric esters of the optically active alcohols, whereas the shorter chain length of the alcohol tends to give lower separation factor (
α) on the same column. The longest chain length of alcohol used in this study is 2-octanol and its ester shows the highest α on the Rtx-2330 capillary column.
Thus, the four thermodynamically related column constants (
a,
b,
c and
d) of
Eq. (1) for
R- and
S-AHFAs standard are determined.
ln
k′=a+bn+
c
T
+
dn
T
where
k′ is the retention factor,
n the equivalent carbon number and
T the absolute temperature. This equation is used to estimate the equivalent
n, and also subsequently used to identify and determine the configuration of AHFAs in wool wax without using a standard AHFA as a reference.</abstract><pub>Elsevier B.V</pub><doi>10.1016/S0003-2670(02)00400-2</doi><tpages>9</tpages></addata></record> |
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| identifier | ISSN: 0003-2670 |
| ispartof | Analytica Chimica Acta, 2002-08, Vol.465 (1), p.299-307 |
| issn | 0003-2670 1873-4324 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_17817623 |
| source | Access via ScienceDirect (Elsevier) |
| subjects | Diasteriomer Enantiomer Gas chromatography Hydroxy acid ester Resolution |
| title | Gas chromatographic separation of R/ S-α-hydroxy fatty acid esters |
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