Structure based medicinal chemistry-driven strategy to design substituted dihydropyrimidines as potential antileishmanial agents

In an attempt to explore novel and more potent antileishmanial compounds to diversify the current inhibitors, we pursued a medicinal chemistry-driven strategy to synthesize novel scaffolds with common pharmacophoric features of dihydropyrimidine and chalcone as current investigational antileishmania...

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Veröffentlicht in:European journal of medicinal chemistry 2016-06, Vol.115, p.230-244
Hauptverfasser: Rashid, Umer, Sultana, Riffat, Shaheen, Nargis, Hassan, Syed Fahad, Yaqoob, Farhana, Ahmad, Muhammad Jawad, Iftikhar, Fatima, Sultana, Nighat, Asghar, Saba, Yasinzai, Masoom, Ansari, Farzana Latif, Qureshi, Naveeda Akhter
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Sprache:eng
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